A manifesto on the preservation of sexual function in women and girls with cancer.
A manifesto on the preservation of sexual function in women and girls with cancer.
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DOI：
10.1016/j.ajog.2015.03.039
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发表时间：
2015-08
影响因子：
9.8
通讯作者：
Matthews AC
中科院分区：
文献类型：
--
作者：
Lindau ST;Abramsohn EM;Matthews AC
影响癌症幸存者的女性的恶性肿瘤通常起源于、侵袭和/或转移到性器官，包括卵巢、子宫体、子宫颈、阴道、外阴、输卵管、肛门、直肠、乳房(S)和大脑。女性在患有直接影响性器官的癌症的人口中占大多数(在数量和比例上)。在最常受癌症影响的年龄段中，大多数女性在确诊前一年性生活活跃，其中包括大多数有伴侣的更年期女性。在女性癌症幸存者中，绝大多数人的癌症是通过局部或系统治疗来治疗的，这些治疗会导致性器官被切除、妥协或破坏。此外，女性癌症幸存者经常经历突然或过早的绝经，要么直接通过手术、放射或其他治疗，要么间接通过女性性激素或其他神经内分泌生理中断。对许多女性患者来说，癌症治疗会对身体、心理和社会功能的其他方面产生短期和长期的影响，这些方面可能会干扰正常的性功能；这些影响包括疼痛、抑郁和焦虑；疲劳和睡眠中断；体重和身体形象的变化；疤痕、正常皮肤感觉的丧失和其他皮肤变化；体味的变化；造口和失去正常的肠道和膀胱功能；淋巴水肿，以及亲密伙伴关系紧张和其他社会角色的变化。尽管如此，接受癌症治疗的女性患者在接受癌症治疗后，没有得到足够的咨询、支持或治疗来维持或恢复性功能。
Malignancies that affect females who survive cancer commonly originate in, invade, and/or metastasize to the sexual organs, including the ovaries, uterine corpus, uterine cervix, vagina, vulva, fallopian tubes, anus, rectum, breast(s), and brain. Females comprise most of the population (in number and proportion) with cancers that directly affect the sexual organs. Most females in the age groups most commonly affected by cancer are sexually active in the year before diagnosis, which includes most menopausal women who have a partner. Among female cancer survivors, the vast majority have cancers that are treated with local or systemic therapies that result in removal, compromise, or destruction of the sexual organs. Additionally, female cancer survivors often experience abrupt or premature onset of menopause, either directly with surgery, radiation, or other treatments or indirectly through disruption of female sex hormone or other neuroendocrine physiology. For many female patients, cancer treatment has short-term and long-lasting effects on other aspects of physical, psychological, and social functioning that can interfere with normal sexual function; these effects include pain, depression, and anxiety; fatigue and sleep disruption; changes in weight and body image; scars, loss of normal skin sensation, and other skin changes; changes in bodily odors; ostomies and loss of normal bowel and bladder function; lymphedema, and strained intimate partnerships and other changes in social roles. In spite of these facts, female patients who are treated for cancer receive insufficient counseling, support, or treatment to preserve or regain sexual function after cancer treatment.