The evolution of the testis transcriptome in pregnant male pipefishes and seahorses
The evolution of the testis transcriptome in pregnant male pipefishes and seahorses
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DOI：
10.1111/evo.14579
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发表时间：
2022-07
期刊：
影响因子：
3.3
通讯作者：
B. Johnson;Andrew P. Anderson;C. M. Small;Emily Rose;S. Flanagan;Corey Hendrickson-Rose;Adam G Jones
中科院分区：
文献类型：
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作者：
B. Johnson;Andrew P. Anderson;C. M. Small;Emily Rose;S. Flanagan;Corey Hendrickson-Rose;Adam G Jones
在许多动物中，精子竞争和性冲突被认为推动了雄性特异性基因的快速进化，特别是那些在睾丸中表达的基因。一个潜在的例外发生在雄性怀孕的管鱼身上，雌性将卵子转移给雄性，消除了睾丸参与这些过程。本研究表明，与其他鱼类相比，管鱼和海马（合颌纲）中睾丸相关基因的分子进化速率和表达模式存在显著差异。在合鱼体内，与睾丸或精子功能相关的基因相比，它们在产卵和产卵鱼类中的同源基因选择更弱。对睾丸转录组中基因周转和表达的评估表明，与其他鱼类相比，合颌鱼已经失去了睾丸转录组中重要基因类别的表达（或显着降低了表达）。我们的研究结果表明，超过5000万年的男性怀孕已经从分子军备竞赛中消除了合颌体睾丸，而分子军备竞赛推动了其他分类群中男性生殖基因的快速进化。
In many animals, sperm competition and sexual conflict are thought to drive the rapid evolution of male‐specific genes, especially those expressed in the testes. A potential exception occurs in the male pregnant pipefishes, where females transfer eggs to the males, eliminating testes from participating in these processes. Here, we show that testis‐related genes differ dramatically in their rates of molecular evolution and expression patterns in pipefishes and seahorses (Syngnathidae) compared to other fish. Genes involved in testis or sperm function within syngnathids experience weaker selection in comparison to their orthologs in spawning and livebearing fishes. An assessment of gene turnover and expression in the testis transcriptome suggests that syngnathids have lost (or significantly reduced expression of) important classes of genes from their testis transcriptomes compared to other fish. Our results indicate that more than 50 million years of male pregnancy have removed syngnathid testes from the molecular arms race that drives the rapid evolution of male reproductive genes in other taxa.