RELATION OF PYRAMIDAL TRACT ACTIVITY TO FORCE EXERTED DURING VOLUNTARY MOVEMENT
RELATION OF PYRAMIDAL TRACT ACTIVITY TO FORCE EXERTED DURING VOLUNTARY MOVEMENT
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DOI：
10.1152/jn.1968.31.1.14
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发表时间：
1968-01-01
影响因子：
2.5
通讯作者：
EVARTS, EV
中科院分区：
文献类型：
--
作者：
EVARTS, EV
猴子们被训练进行手腕的交替屈伸运动，以获得果汁奖励。只有当2个连续位移（屈曲后伸展，反之亦然）的持续时间在400和700毫秒之间时，才能提供奖励。在某些时候，负荷对抗屈曲，因此，所需持续时间的屈肌和伸肌位移都涉及屈肌肌肉组织的活动和屈肌力的施加。在其他时候，负荷反对延长，要求屈肌和伸肌位移与伸肌力。因此，力与位移方向无关，可以确定中央前运动皮层记录的与这种运动相关的锥体束神经元（PTN）放电是否与力的方向或位移的方向有关。对于大多数PTNs，放电频率主要与力（F）和dF/dt相关，仅与位移方向相关。一些与力无关的PTNs与位移的方向相关，但与位移的细节无关，而许多其他PTNs与施加的力的细节相关。
Monkeys were trained to carry out alternate flexion-extension movements of the wrist for a fruit juice reward. Reward was delivered only when the durations of 2 successive displacements (flexion followed by extension or vice versa) fell between 400 and 700 msec. At certain times a load opposed flexion and, as a result, both the flexor and the extensor displacements of the required duration involved activity of the flexor musculature and exertion of flexor force. At other times the load opposed extension, requiring that both flexor and extensor displacements be associated with extensor force. Force was thus dissociated from direction of displacement, and it was possible to determine whether pyramidal tract neuron (PTN) discharges recorded from the precentral motor cortex in association with this movement were related to direction of force or to direction of displacement. For the majority of PTNs, discharge frequency was related primarily to the force (F) and dF/dt, and was only secondarily related to the direction of displacement. Some PTNs which were unrelated to force were related to the direction of displacement, but not to the fine details of the displacement in the way that numerous other PTNs were related to the fine details of applied force.