Development of V2-deleted trimeric envelope vaccine candidates from human immunodeficiency virus type 1 (HIV-1) subtypes B and C
Development of V2-deleted trimeric envelope vaccine candidates from human immunodeficiency virus type 1 (HIV-1) subtypes B and C
复制标题
DOI：
10.1016/j.micinf.2005.07.018
复制
发表时间：
2005-11-01
影响因子：
5.8
通讯作者：
Rappuoli, R
中科院分区：
文献类型：
--
作者：
Barnett, SW;Srivastava, IK;Rappuoli, R
对艾滋病毒/艾滋病疫苗的迫切需要要求在临床环境中采用和评估多种战略。从乙型和丙型人类免疫缺陷病毒1型（HIV-1）毒株中提取出v2环缺失三聚包膜（Env）免疫原（蛋白质和DNA），用于与其他HIV抗原、佐剂和递送剂进行正在进行和未来的临床评估。(c) 2005 Elsevier SAS。版权所有。
The urgent need for a vaccine against HIV/AIDS requires that multiple strategies be employed and evaluated in a clinical setting. V2-loop deleted trimeric envelope (Env) immunogens (protein and DNA) from subtypes B and C human immunodeficiency virus type 1 (HIV-1) strains were produced for ongoing and future clinical evaluations with other HIV antigens, adjuvants and deliveries. (c) 2005 Elsevier SAS. All rights reserved.