DISTRIBUTION OF DIFFERENT FIBER TYPES IN HUMAN SKELETAL-MUSCLES - FIBER TYPE ARRANGEMENT IN M-VASTUS LATERALIS FROM 3 GROUPS OF HEALTHY-MEN BETWEEN 15 AND 83 YEARS

DISTRIBUTION OF DIFFERENT FIBER TYPES IN HUMAN SKELETAL-MUSCLES - FIBER TYPE ARRANGEMENT IN M-VASTUS LATERALIS FROM 3 GROUPS OF HEALTHY-MEN BETWEEN 15 AND 83 YEARS
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DOI:
10.1016/0022-510x(86)90009-2
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发表时间:
1986-02-01
影响因子:
4.4
通讯作者:
SJOSTROM, M
SJOSTROM, M
中科院分区:
医学3区
文献类型:
--
作者:
LEXELL, J;DOWNHAM, D;SJOSTROM, M

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The effects of age on the fibre type arrangement in the human muscle m. vastus lateralis were studied. There were 10, 6 and 8 healthy men in the three age-groups with means 24, 52 and 77 years, respectively. For each fascicle considered, the numbers of type 1 (ST) and type 2 (FT) fibres on the boundary and internally, and the numbers of enclosed fibres of either type, were counted. The randomness of the fibre type arrangement was considered in terms of the numbers of enclosed fibres and assessed by a Monte Carlo significance test. Fibre type grouping was shown to increase with increasing age. The proportion of type 2 fibres on the boundary of a fascicle was consistently greater than internally, but the difference was less pronounced in the old group. It is argued that the process of denervation and reinnervation of individual fibres has started before the age of 50, is a major factor in a progressive reduction of fibres with increasing age and is probably caused by a continuous loss of motor neurons in the spinal cord.