Alpha-glucosidase inhibitory and antioxidant activities of Vietnamese edible plants and their relationships with polyphenol contents
Alpha-glucosidase inhibitory and antioxidant activities of Vietnamese edible plants and their relationships with polyphenol contents
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DOI：
10.3177/jnsv.53.267
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发表时间：
2007-06-01
影响因子：
1.6
通讯作者：
Van Chuyen, Nguyen
中科院分区：
文献类型：
--
作者：
Mai, Truong Tuyet;Thu, Nghiem Nguyet;Van Chuyen, Nguyen
利用多酚类植物的有益生物效应来预防和治疗非传染性疾病已引起营养科学家越来越大的兴趣。本文研究了越南28种常见食用植物（饮料植物、食用野菜、草本植物和深绿色蔬菜）的水提液和甲醇提液的体外抑制和抗氧化活性。用Folin-Ciocalteu法测定提取物中多酚的含量，并用儿茶素当量计算。用于制作饮料的植物提取物显示出最高的抑制a-葡萄糖苷酶和抗氧化剂活性，其次是食用野菜、草药和深绿色蔬菜。这28种可食植物的a-葡萄糖苷酶抑制活性、抗氧化活性与多酚含量呈正相关。与番石榴叶提取物相似或优于番石榴叶提取物的4种新材料（Syzygium zeylanicum、Cleistocalyx operculatits、Horsfieldia amygdalina和Careya arborea）在冻干终浓度为0.8 mg /mL溶液时表现出较高的a-葡萄糖苷酶抑制活性（分别为93、76、68和671%），在冻干终浓度为30 μ g /mL溶液时表现出较高的抗氧化活性（分别为85、87、78和80%）。这四种可食用植物的多酚含量均显著较高（儿茶素含量分别为251.7、146.6、136.6和168.6 mg /g干重）。因此，这四种材料可能是抑制α -葡萄糖苷酶和抗氧化剂的新来源，适合在未来作为功能食品使用。
The prevention and treatment of non-communicable diseases by using the beneficial biological effects of polyphenolic plants have attracted increasing interest from nutritional scientists. The a-glucosidase inhibitory and antioxidant activities of aqueous and methanolic extracts from 28 common Vietnamese edible plants, comprising 4 groups (plants used for making drinks, edible wild vegetables, herbs, and dark green vegetables), were investigated in vitro. The polyphenol contents of these extracts were determined by the Folin-Ciocalteu method and calculated as catechin equivalents. The extracts from plants used for making drinks showed the highest activities for both a-glucosidase inhibition and as antioxidants, followed by edible wild vegetables, herbs, and dark green vegetables. Positive relationships among a-glucosidase inhibitory activities, antioxidant activities and polyphenol contents of these 2 8 edible plants were found in both aqueous and methanolic extracts. Four new promising materials that are similar to or better than guava leaf extract, including Syzygium zeylanicum, Cleistocalyx operculatits, Horsfieldia amygdalina and Careya arborea demonstrated high a-glucosidase inhibitory activity (93, 76, 68 and 671%, respectively) at the final concentration of 0.8 mg lyophilized material/mL solution and antioxidant activity (85, 87, 78 and 80%, respectively) at the final concentration of 30 mu g lyophilized material/mL solution. These four edible plants contained significantly high polyphenol contents (equivalent to 251.7, 146.6, 136.6 and 168.6 mg of catechin/g dry weight, respectively). Thus, these four materials might be possible new sources of alpha-glucosidase inhibition and antioxidants suitable for use as functional foods in the future.