Direct Pulp Capping: Which is the Most Effective Biomaterial? A Retrospective Clinical Study
Direct Pulp Capping: Which is the Most Effective Biomaterial? A Retrospective Clinical Study
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DOI：
10.3390/ma12203382
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发表时间：
2019-10-01
期刊：
影响因子：
3.4
通讯作者：
Ferreira, Manuel M.
中科院分区：
文献类型：
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作者：
Paula, Anabela;Carrilho, Eunice;Ferreira, Manuel M.
(1)背景：最近出现了Biodentine(TM)等三钙硅酸盐水泥。这种生物材料以氢氧化钙为基础，具有矿物集合体三氧化二骨水泥的特性，但具有更适合其应用的紧固时间和其他临床优势。(2)方法：对20例患者进行回顾性临床研究，包括有无牙髓炎症相容症状的临床评价、根尖周组织的放射学评价以及支持Biodentine(TM)和WhiteProRoot((R))MTA盖髓疗法的冠脉修复体的结构变化。(3)结果：本临床研究显示，矿质三氧化二骨水泥和硅酸钙骨水泥6个月的成功率相近，分别为100%和95%。两种生物材料之间以及它们与各种临床环境之间，即手术野的绝对隔离、暴露的大小、暴露的病因学，甚至所使用的修复材料的类型，在统计学上没有显著差异。(4)结论：Biodentine(TM)对牙本质桥的形成有一定的治疗作用，并伴有轻微的炎症征象，临床成功率较高，提示其在人牙髓直接盖髓中具有与金标准材料相似的安全有效的应用前景。
(1) Background: Recently, tricalcium silicate cements, such as Biodentine (TM), have emerged. This biomaterial has a calcium hydroxide base and characteristics like mineral aggregate trioxide cements, but has tightening times that are substantially more suitable for their application and other clinical advantages. (2) Methods: A retrospective clinical study was conducted with 20 patients, which included a clinical evaluation of the presence or absence of pulp inflammation compatible symptoms, radiographic evaluation of the periapical tissues, and structural alterations of the coronary restoration that supports pulp capping therapies with Biodentine (TM) and WhiteProRoot((R))MTA. (3) Results: This clinical study revealed similar success rates between mineral trioxide cement and tricalcium silicates cements at 6 months, with 100% and 95% success rates, respectively. There were no statistically significant differences between both biomaterials and between these and the various clinical circumstances, namely the absolute isolation of the operating field, exposure size, the aetiology of exposure, and even the type of restorative material used. (4) Conclusions: Biodentine (TM) demonstrated a therapeutic effect on the formation of a dentin bridge accompanied by slight inflammatory signs, with a high clinical success rate, indicating the possibility of its effective and safe use in dental pulp direct capping in humans, similar to the gold standard material.