A weight-gain-for-gestational-age z score chart for the assessment of maternal weight gain in pregnancy
A weight-gain-for-gestational-age z score chart for the assessment of maternal weight gain in pregnancy
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DOI：
10.3945/ajcn.112.051706
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发表时间：
2013-05-01
影响因子：
7.1
通讯作者：
Bodnar, Lisa M.
中科院分区：
文献类型：
--
作者：
Hutcheon, Jennifer A.;Platt, Robert W.;Bodnar, Lisa M.
背景资料：为了建立孕妇体重增加与围产期健康之间的无偏关系，需要对孕妇体重增加进行分类，与孕龄无关。目的：本研究的目的是创建一个体重增加遗忘年龄百分位数和z评分图，以描述当代美国妇女队列中孕妇整个妊娠期体重增加的平均值、标准差和选定的百分比。设计：研究人群来自1998-2008年在宾夕法尼亚州匹兹堡的Magee-Womens医院分娩的体重正常的无并发症单胎妊娠妇女。分析基于随机选择的648名妇女的子集，这些妇女通过病历记录提取获得了连续的产前体重测量结果（6727次体重测量）。结果：通过使用随机效应回归模型估计整个妊娠期间母体体重增加的模式。估计值用于创建具有平滑平均值的图表，结论：这张图表使研究人员能够将总体重增加表示为年龄标准化的z评分，该评分可用于流行病学分析，以研究妊娠体重增加与独立于胎龄的不良或生理妊娠结局之间的相关性。美国临床营养杂志2013;97：1062-7。
Background: To establish the unbiased relation between maternal weight gain in pregnancy and perinatal health, a classification for maternal weight gain is needed that is uncorrelated with gestational age.Objective: The goal of this study was to create a weight-gain-forgestational-age percentile and z score chart to describe the mean, SD, and selected percentiles of maternal weight gain throughout pregnancy in a contemporary cohort of US women.Design: The study population was drawn from normal-weight women with uncomplicated, singleton pregnancies who delivered at the Magee-Womens Hospital in Pittsburgh, PA, 1998-2008. Analyses were based on a randomly selected subset of 648 women for whom serial prenatal weight measurements were available through medical chart record abstraction (6727 weight measurements).Results: The pattern of maternal weight gain throughout gestation was estimated by using a random-effects regression model, The estimates were used to create a chart with the smoothed means, percentiles, and SDs of gestational weight gain for each week of pregnancy.Conclusion: This chart allows researchers to express total weight gain as an age-standardized z score, which can be used in epidemiologic analyses to study the association between pregnancy weight gain and adverse or physiologic pregnancy outcomes independent of gestational age. Am J Clin Nutr 2013;97:1062-7.