Neurovascular coupling in the human somatosensory cortex: a single trial study
Neurovascular coupling in the human somatosensory cortex: a single trial study
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DOI：
10.1097/wnr.0b013e3283406615
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发表时间：
2010-12-08
期刊：
影响因子：
1.7
通讯作者：
Minabe, Yoshio
中科院分区：
文献类型：
--
作者：
Kikuchi, Mitsuru;Shitamichi, Kiyomi;Minabe, Yoshio
高频振荡与局部脑血流动力学变化密切相关。在这里，我们研究了这种神经血管耦合在人类的电刺激右正中神经。在一项单次试验研究中，我们同时记录了近红外光谱和全头脑磁图（MEG）的脑神经元振荡的躯体感觉皮层的血流动力学波动。6名志愿者的结果表明，在刺激条件下，β或γ波段功率的神经波动与血流动力学波动相关。这些相关性在5-7秒的时间延迟下是显著的。这项研究提供了新的直接证据表明，血流动力学的开始滞后于特定的神经振荡在人类清醒的条件下，使用非侵入性的方法在几秒钟的顺序。NeuroReport 21：1106-1110（C）2010年威科健康垂直酒吧Lippincott威廉姆斯&威尔金斯。
Oscillations in the higher frequency range are closely related to regional brain hemodynamic changes. Here we investigated this neurovascular coupling in humans in response to electrical stimulation of the right median nerve. In a single-trial study, we simultaneously recorded hemodynamic fluctuations in the somatosensory cortex by near infrared spectroscopy and brain neuronal oscillations by whole-head magnetoencephalography (MEG). The results from six volunteers showed that neural fluctuations at beta or gamma-band power were correlated with hemodynamic fluctuation during stimulus conditions. These correlations were prominent with a time delay of 5-7 s. This study provides new direct evidence that hemodynamic onset lags specific neural oscillations in the order of seconds in human awake conditions using noninvasive methods. NeuroReport 21:1106-1110 (C) 2010 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.