Synthesis and Structure−Activity Relationships of an Orally Available and Long-Acting Analgesic Peptide, Nα-Amidino-Tyr-d-Arg-Phe-MeβAla-OH (ADAMB)
Synthesis and Structure−Activity Relationships of an Orally Available and Long-Acting Analgesic Peptide, Nα-Amidino-Tyr-d-Arg-Phe-MeβAla-OH (ADAMB)
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口服长效镇痛肽 Nα-脒基-Tyr-d-Arg-Phe-MeβAla-OH (ADAMB) 的合成及其构效关系
DOI：
10.1021/jm010357t
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发表时间：
2002
影响因子：
7.3
通讯作者：
T. Morikawa
中科院分区：
文献类型：
--
作者：
T. Ogawa;T. Miyamae;K. Murayama;K. Okuyama;T. Okayama;M. Hagiwara;S. Sakurada;T. Morikawa
在n - α-氨基- tyr1 -d- arg - ph - me - β ala - oh （ADAMB）结构的基础上，设计了一种新的dermorphin四肽n - α-氨基- tyr -d- arg - ph - gly -…
A novel dermorphin tetrapeptide Nα-amidino-Tyr-d-Arg-Phe-MeβAla-OH (ADAMB) was designed based on the structures of several dermorphin tetrapeptide analogues, including Nα-amidino-Tyr-d-Arg-Phe-Gly-...