COMPARISON OF GASTRIC INTRAMUCOSAL PH AND STANDARD PERFUSIONAL MEASUREMENTS IN PEDIATRIC SEPTIC SHOCK
COMPARISON OF GASTRIC INTRAMUCOSAL PH AND STANDARD PERFUSIONAL MEASUREMENTS IN PEDIATRIC SEPTIC SHOCK
复制标题
DOI：
10.1378/chest.108.1.220
复制
发表时间：
1995-07-01
期刊：
影响因子：
9.6
通讯作者：
WILKINSON, JD
中科院分区：
文献类型：
--
作者：
KRAFTEJACOBS, B;CARVER, J;WILKINSON, JD
目的：探讨胃张力计作为儿童感染性休克发病率和死亡率的早期指标的应用价值。设计：前瞻性临床研究。环境：多学科儿科ICU。患者：8例小儿感染性休克危重症患者，肺动脉和胃张力计导管就位。干预措施：每4小时测量一次标准灌注数据，包括心脏指数、氧含量（动脉、混合静脉）、供氧量、耗氧量、尿量、毛细血管再充血和乳酸值。通过同时测胃粘膜内Pco(2) （Pico(2)）计算粘膜内pH （pHi）。比较幸存者和非幸存者的平均pHi值。通过回归分析将血压计数据与标准灌注数据进行比较。低pHi值(
Objective: To examine the utility of gastric tonometry as an early indicator of morbidity and mortality in pediatric patients with septic shock.Design: Prospective clinical study.Setting: Multidisciplinary pediatric ICU.Patients: Eight critically ill pediatric patients with septic shock and with pulmonary artery and gastric tonometry catheters in place.Interventions: Standard perfusional data including cardiac index, oxygen content (arterial, mixed venous), oxygen delivery, oxygen consumption, urine output, capillary refill, and lactate value were measured every 4 h. Intramucosal pH (pHi) was calculated from simultaneous tonometric measurements of gastric intramucosal Pco(2) (Pico(2)). Mean pHi values were compared between survivors and nonsurvivors. Tonometric data were compared with standard perfusional data by regression analysis. Low pHi values (