Clinical and macroscopic correlates of minicolumnar pathology in autism
Clinical and macroscopic correlates of minicolumnar pathology in autism
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DOI：
10.1177/088307380201700908
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发表时间：
2002-09-01
影响因子：
1.9
通讯作者：
Brown, C
中科院分区：
文献类型：
--
作者：
Casanova, MF;Buxhoeveden, DP;Brown, C
所有皮质下排列主要是核排列。大脑皮层是大脑中最先进化出放射状和层状排列的细胞的部分。由此产生的模块化安排是基于细胞微柱：一个独立的生态系统的连接传入，传出，和神经元连接。最近，自闭症患者的细胞微柱被发现异常。本文涉及不同方面的细胞minicolumn和大规模的神经元组件潜在的研究技术及其在临床实践中的应用。
All subcortical arrangements are primarily nuclear in type. The cortex has been the first part of the brain to evolve a radial and laminar arrangement of cells. The resultant modular arrangement is based on the cell minicolumn: a self-contained ecosystem of connectivity linking afferent, efferent, and inerneuronal connections. Recently, the cell minicolumn has been found to be abnormal in patients with autism. This article relates different aspects of the cell minicolumn and larger-scale neuronal assemblies to potential research techniques and their application to clinical practice.