THE COLOR CENTER IN THE CEREBRAL-CORTEX OF MAN
THE COLOR CENTER IN THE CEREBRAL-CORTEX OF MAN
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DOI：
10.1038/340386a0
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发表时间：
1989-08-03
期刊：
影响因子：
64.8
通讯作者：
FRACKOWIAK, RSJ
中科院分区：
文献类型：
--
作者：
LUECK, CJ;ZEKI, S;FRACKOWIAK, RSJ
解剖学和生理学研究表明，猕猴大脑的前皮层有一个专门处理颜色的区域（V4区）。本世纪初，关于人类大脑中存在色彩中心的临床证据被驳回了，因为其他视觉缺陷与色觉缺陷有关。然而，自从证明了猕猴皮层的功能特化以来，基于视觉皮层有类似病变的患者，对人类的颜色中心问题进行了重新研究。为了研究正常人的色彩中心，我们使用了正电子发射断层扫描（PET）技术，该技术测量了大脑皮层活动增加导致的血流量增加。对观看彩色和黑白显示器的受试者进行PET扫描的结果进行比较，发现了正常人大脑皮层中专门负责色觉的区域。
ANATOMICAL and physiological studies have shown that there is an area specialized for the processing of colour (area V4) in the prestriate cortex of macaque monkey brain1. Earlier this century, suggestive clinical evidence for a colour centre in the brain of man2,3was dismissed4-8because of the association of other visual defects with the defects in colour vision4,5,7. However, since the demonstration of functional specialization in the macaque cortex9, the question of a colour centre in man has been reinvestigated,based on patients with similar lesions in the visual cortex10-12. In order to study the colour centre in normal human subjects, we used the technique of positron emission tomography (PET), which measures increases in blood flow resulting from increased activity in the cerebral cortex. A comparison of the results of PET scans of subjects viewing multi-coloured and black-and-white displays has identified a region of normal human cerebral cortex specialized for colour vision.