CELL LIFE CYCLE DURING EARLY EMBRYOGENESIS OF MOUSE

CELL LIFE CYCLE DURING EARLY EMBRYOGENESIS OF MOUSE
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DOI:
10.1016/0014-4827(70)90630-0
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发表时间:
1970-01-01
影响因子:
3.7
通讯作者:
PRESCOTT, DM
PRESCOTT, DM
中科院分区:
医学3区
文献类型:
--
作者:
GAMOW, EI;PRESCOTT, DM

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~ 3 H-胸腺嘧啶核苷脉冲15分钟后DNA合成的放射自显影标记模式表明,小鼠胚胎在2-和16-细胞期之间的细胞生命周期缺乏G1期。在桑椹胚和胚泡阶段,80%的细胞被15分钟的3 H-胸苷脉冲标记,表明GI期非常短,在这些发育的后期可能不存在。在两细胞期之后,G2期非常短。
The autoradiographic labeling patterns for DNA synthesis after a 15 min pulse of3H-thymidine show that the cell life cycles for mouse embryos between the two- and 16-cell stages lack a G1 period. During morulae and blastocyst stages 80 % of the cells are labeled by a 15 min pulse of3H-thymidine, demonstrating that the GI period is very short and possibly absent during these later stages of development. Subsequent to the two-cell stage, the G2 period is very short.