Evaluating the Efficacy of the Drinks:Ration Mobile App to Reduce Alcohol Consumption in a Help-Seeking Military Veteran Population: Randomized Controlled Trial.
Evaluating the Efficacy of the Drinks:Ration Mobile App to Reduce Alcohol Consumption in a Help-Seeking Military Veteran Population: Randomized Controlled Trial.
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DOI：
10.2196/38991
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发表时间：
2022-06-20
影响因子：
5
通讯作者：
Murphy, Dominic
中科院分区：
文献类型：
--
作者：
Leightley, Daniel;Williamson, Charlotte;Rona, Roberto J;Carr, Ewan;Shearer, James;Davis, Jordan P;Simms, Amos;Fear, Nicola T;Goodwin, Laura;Murphy, Dominic
酒精滥用在英国武装部队(AF)中的比例高于普通人群。研究表明，酒精滥用在个人退役后仍然存在，对于那些因精神健康困难而寻求帮助的人来说，这一点尤其明显。尽管如此，还没有关于测试个性化支持英国房颤的移动减少酒精干预的工作。为了解决这一差距，我们调查了通过手机应用程序提供的为期28天的短暂酒精干预在减少寻求心理健康困难帮助的英国退伍军人每周自报酒精消费量方面的有效性。我们进行了两组受试者随机对照试验(RCT)。我们比较了一款包含旨在增强参与者动机和个性化信息的互动功能的移动应用程序(干预臂)和一个仅提供政府饮酒指导的版本(控制臂)。如果成年人曾在英国空军服役，目前正在接受或已经接受精神健康症状的临床支持，并每周消费14个单位(约112克酒精)或更多酒精，则符合资格。参与者接受干预或对照移动应用程序(1：1比例)。主要结果是在基线和第84天之间使用有效的酒精消费时间线回访(TLFB)评估自我报告的每周饮酒量的变化(之前7天)，次要结果是探索酒精使用障碍识别测试(AUDIT)分数的自我报告的变化。在2020年10月至2021年4月期间，2708人被邀请参加，其中2531人(93.5%)没有回答，54人(2%)不合格，123人(4.5%)回答并随机分配(62人，50.4%，干预；61人，49.6%，对照)。在第84天，干预组的41名参与者(66.1%)和对照组的37名参与者(60.7%)完成了初步结果评估。在基线和第84天之间，对照组每周饮酒量减少了-10.5(95%CI-19.5至-1.5)个单位，干预组每周饮酒量减少了-28.2(95%CI-36.9至-19.5)个单位(P=0.003，Cohen d=0.35)。我们还发现，干预组的审计得分显著降低，为-3.9(95%CI-6.2至-1.6)(Cohen d=0.48)。我们的主要和次要影响不会持续更长的时间(第168天)。在试验过程中发现了两种不良反应。这项研究通过手机应用程序对英国危险饮酒退伍军人的求助样本进行了为期28天的全自动短暂酒精干预。我们发现，与只接受指导的参与者相比，接受饮料：配给的参与者减少了更多的酒精消耗(在第84天)。在短期内，我们发现饮料：定量配给在减少寻求帮助的退伍军人的酒精消耗量方面是有效的。ClinicalTrials.gov NCT04494594；https://tinyurl.com/34em6n9f rr2-10.2196/19720
Alcohol misuse is higher in the UK armed forces (AF) than in the general population. Research demonstrates that alcohol misuse persists after an individual leaves service, and this is notably the case for those who are seeking help for a mental health difficulty. Despite this, there is no work on testing a mobile alcohol reduction intervention that is personalized to support the UK AF. To address this gap, we investigated the efficacy of a 28-day brief alcohol intervention delivered via a mobile app in reducing weekly self-reported alcohol consumption among UK veterans seeking help for mental health difficulties. We performed a 2-arm participant-blinded randomized controlled trial (RCT). We compared a mobile app that included interactive features designed to enhance participants’ motivation and personalized messaging (intervention arm) with a version that provided government guidance on alcohol consumption only (control arm). Adults were eligible if they had served in the UK AF, were currently receiving or had received clinical support for mental health symptoms, and consumed 14 units (approximately 112 g of ethanol) or more of alcohol per week. Participants received the intervention or the control mobile app (1:1 ratio). The primary outcome was a change in self-reported weekly alcohol consumption between baseline and day 84 assessed using the validated Timeline Follow Back for Alcohol Consumption (TLFB) (prior 7 days), with a secondary outcome exploring self-reported change in the Alcohol Use Disorder Identification Test (AUDIT) score. Between October 2020 and April 2021, 2708 individuals were invited to take part, of which 2531 (93.5%) did not respond, 54 (2%) were ineligible, and 123 (4.5%) responded and were randomly allocated (62, 50.4%, intervention; 61, 49.6%, control). At day 84, 41 (66.1%) participants in the intervention arm and 37 (60.7%) in the control arm completed the primary outcome assessment. Between baseline and day 84, weekly alcohol consumption reduced by –10.5 (95% CI –19.5 to –1.5) units in the control arm and –28.2 (95% CI –36.9 to –19.5) units in the intervention arm (P=.003, Cohen d=0.35). We also found a significant reduction in the AUDIT score of –3.9 (95% CI –6.2 to –1.6) in the intervention arm (Cohen d=0.48). Our primary and secondary effects did not persist over the longer term (day 168). Two adverse events were detected during the trial. This study examined the efficacy of a fully automated 28-day brief alcohol intervention delivered via a mobile app in a help-seeking sample of UK veterans with hazardous alcohol consumption. We found that participants receiving Drinks:Ration reduced their alcohol consumption more than participants receiving guidance only (at day 84). In the short term, we found Drinks:Ration is efficacious in reducing alcohol consumption in help-seeking veterans. ClinicalTrials.gov NCT04494594; https://tinyurl.com/34em6n9f RR2-10.2196/19720