Comparison of peripapillary and subfoveal choroidal thickness in normal versus primary open-angle glaucoma (POAG) subjects using spectral domain optical coherence tomography (SD-OCT) and swept source optical coherence tomography (SS-OCT)
Comparison of peripapillary and subfoveal choroidal thickness in normal versus primary open-angle glaucoma (POAG) subjects using spectral domain optical coherence tomography (SD-OCT) and swept source optical coherence tomography (SS-OCT)
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DOI：
10.1136/bmjophth-2018-000258
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发表时间：
2019-01-01
影响因子：
2.4
通讯作者：
Senthil, Sirisha
中科院分区：
文献类型：
--
作者：
Komma, Swetha;Chhablani, Jay;Senthil, Sirisha
目的探讨原发性开角型青光眼（POAG）患者的脉络膜厚度（CT）与正常人的差异，并比较光谱域光学相干断层扫描（SD-OCT）与扫源光学相干断层扫描（SS-OCT）的CT测量结果。本横断面观察研究包括17例POAG患者的25只眼（病例）和20例正常人的31只眼（对照）。所有患者均行完整眼科检查、增强深度成像、SD-OCT和SS-OCT检查。在对照组和病例中，在黄斑和乳头周围区域的7个预定点进行CT测量并进行比较。结果除下乳头周围区外，两组患者的SS-OCT乳头周围区和黄斑区脉络膜均较SD-OCT明显增厚。在SD-OCT上，青光眼乳头周围和黄斑区域的CT与对照组比较差异无统计学意义（p < 0.05），但在SS-OCT上，青光眼乳头周围区域的CT较对照组明显增厚（p < 0.05）
Objective To elucidate the difference between choroidal thickness (CT) in primary open-angle glaucoma (POAG) and normal subjects and to compare the CT measured using spectral domain optical coherence tomography (SD-OCT) and swept source optical coherence tomography (SS-OCT). Methods and analysis This cross-sectional observational study included 25 eyes of 17 POAG subjects (cases) and 31 eyes of 20 normal subjects (controls). All the patients underwent complete ophthalmologic examination, enhanced depth imaging, SD-OCT and SS-OCT. In both controls and cases, the CT was measured in seven predetermined points in macular and peripapillary area and were compared. Results Choroid was significantly thicker on SS-OCT compared with SD-OCT in peripapillary and macular area in both cases and controls, except for inferior peripapillary in controls. The CT was not different from glaucoma and controls in peripapillary or macular area on SD-OCT (p>0.05), however, the CT was significantly thicker in glaucoma compared with controls in peripapillary area on SS-OCT (p