Mapping spikes to sensations.
Mapping spikes to sensations.
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DOI：
10.3389/fnins.2011.00125
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发表时间：
2011
影响因子：
4.3
通讯作者：
Jäkel F
中科院分区：
文献类型：
--
作者：
Stüttgen MC;Schwarz C;Jäkel F
在知觉决策任务中进行的单单元记录已经对感觉刺激的神经编码产生了巨大的见解。在这样的实验中，检测或辨别行为（心理测量数据）与感觉神经元中的尖峰序列（神经测量数据）平行观察。通常，用于信息读出的候选神经代码通过以某种方式转换神经测量数据并询问哪种代码的性能最接近心理测量性能而相互竞争。与心理测量性能最匹配的代码被保留为可行的候选者，而其他代码被拒绝。在遵循这一策略时，心理测量数据通常被认为提供了感知敏感性的无偏测量。很少有人承认，心理测量数据是由感觉和非感觉过程的复杂相互作用而产生的，忽视这些过程可能会导致错误估计心理物理敏感性。这又可能导致关于候选神经代码的充分性的错误结论。在这篇综述中，我们首先讨论了随后的神经心理测量比较的神经数据的要求。然后，我们专注于不同的心理物理任务的检测和区分性能的评估和认知过程，可能是其执行的基础。我们进一步讨论可能影响心理测量性能的因素，以及如何检测或避免这些因素。我们相信，这些考虑指出了我们对感知决策过程的理解存在缺陷，因此为未来的研究提供了潜力。
Single-unit recordings conducted during perceptual decision-making tasks have yielded tremendous insights into the neural coding of sensory stimuli. In such experiments, detection or discrimination behavior (the psychometric data) is observed in parallel with spike trains in sensory neurons (the neurometric data). Frequently, candidate neural codes for information read-out are pitted against each other by transforming the neurometric data in some way and asking which code’s performance most closely approximates the psychometric performance. The code that matches the psychometric performance best is retained as a viable candidate and the others are rejected. In following this strategy, psychometric data is often considered to provide an unbiased measure of perceptual sensitivity. It is rarely acknowledged that psychometric data result from a complex interplay of sensory and non-sensory processes and that neglect of these processes may result in misestimating psychophysical sensitivity. This again may lead to erroneous conclusions regarding the adequacy of candidate neural codes. In this review, we first discuss requirements on the neural data for a subsequent neurometric-psychometric comparison. We then focus on different psychophysical tasks for the assessment of detection and discrimination performance and the cognitive processes that may underlie their execution. We discuss further factors that may compromise psychometric performance and how they can be detected or avoided. We believe that these considerations point to shortcomings in our understanding of the processes underlying perceptual decisions, and therefore offer potential for future research.
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DOI：
10.1523/jneurosci.5475-09.2010
发表时间：
2010-04-07
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Bizley JK;Walker KM;King AJ;Schnupp JW
通讯作者：
Schnupp JW
影响因子：
5.3
作者：
Andermann ML;Kerlin AM;Reid RC
通讯作者：
Reid RC
影响因子：
1.7
作者：
Barlow, H B
通讯作者：
Barlow, H B
影响因子：
1.9
作者：
Frederick, Donald E.;Rojas-Libano, Daniel;Kay, Leslie M.
通讯作者：
Kay, Leslie M.
影响因子：
1.9
作者：
Britten, KH;Newsome, WT;Movshon, JA
通讯作者：
Movshon, JA