Practice patterns of infectious disease physicians for management of meningococcal disease.
Practice patterns of infectious disease physicians for management of meningococcal disease.
复制标题
传染病医生管理脑膜炎球菌病的实践模式。
DOI：
10.1097/inf.0b013e31826323a4
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Clark,ThomasA
中科院分区：
文献类型：
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作者：
Terranella,Andrew;Beekmann,SusanE;Polgreen,PhilipM;Cohn,Amanda;Wu,HenryM;Clark,ThomasA
背景：虽然急性细菌性脑膜炎的经验性治疗方案已经确立，但关于脑膜炎球菌病的治疗仍有许多不确定性。在传染病专家中进行了一项调查，以评估脑膜炎球菌病的实践模式和可用性的抗菌药物敏感性测试为奈瑟氏菌menigiagen.Methods：一个在线调查分发给1342儿科和成人传染病专家，以评估常见的做法和意见，关于脑膜炎球菌病的诊断，治疗和预防。专家也被问及有关脑膜炎奈瑟氏球菌在其临床微生物laboratory.Results的抗菌药物敏感性测试的可用性：六百五十名成员回答了调查（48%）。儿科传染病专家比成人专家更有可能使用青霉素作为脑膜炎球菌病的确定性治疗（56%对46%; P= 0.038）。大多数缩小治疗范围的儿科专家报告说，他们只会在确认青霉素敏感性后才改用青霉素（55%），尽管44%的人会根据N。脑膜炎菌种确认超过三分之一的受访者报告说，对N。脑膜炎不是常规检查。也有很大的差异，在补体缺乏症的筛查标准和脑膜炎球菌病的化学预防的做法之间的responders.Conclusions：传染病专家在他们的做法，脑膜炎球菌病的诊断，治疗和预防的几个方面显着不同。对N.脑膜炎在许多实践中并不常规进行。在制定治疗和预防建议时，考虑这些变化将是有用的。
Background:Although empiric treatment regimens for acute bacterial meningitis are well established, there are many uncertainties regarding management of meningococcal disease. A survey was conducted among infectious disease specialists to assess meningococcal disease practice patterns and availability of antimicrobial susceptibility testing for Neisseria menigitidis.Methods:An online survey was distributed to 1342 pediatric and adult infectious disease specialists to assess common practices and opinions regarding the diagnosis, treatment and prevention of meningococcal disease. Specialists were also asked about the availability of antimicrobial susceptibility testing for Neisseria meningitidis at their clinical microbiology laboratory.Results:Six hundred fifty members responded to the survey (48%). Pediatric infectious disease specialists were more likely than adult specialists to use penicillin as definitive therapy for meningococcal disease (56% versus 46%; P= 0.038). Most pediatric specialists who would narrow therapy report that they would only switch to penicillin upon confirmation of penicillin susceptibility (55%), although 44% would narrow therapy based on a N. meningitidis species confirmation alone. More than one third of respondents reported that susceptibility testing for N. meningitidis is not routinely performed. There was also wide variation in complement deficiency screening criteria and meningococcal disease chemoprophylaxis practices among respondents.Conclusions:Infectious disease specialists vary significantly in their practices regarding several aspects of meningococcal disease diagnosis, treatment and prevention. Antimicrobial susceptibility testing for N. meningitidis is not routinely performed in many practices. Consideration of these variations would be useful when developing treatment and prevention recommendations.