Topical Corticosteroid Phobia among Parents of Children with Atopic Eczema in Korea.
Topical Corticosteroid Phobia among Parents of Children with Atopic Eczema in Korea.
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DOI：
10.5021/ad.2015.27.5.499
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发表时间：
2015-10
影响因子：
1.6
通讯作者：
Kim SS
中科院分区：
文献类型：
--
作者：
Lee JY;Her Y;Kim CW;Kim SS
外用皮质类固醇（TCS）是治疗特应性皮炎（AD）的一线药物。然而，由于错误信息，AD儿童的父母对使用TCS存在模糊的恐惧，并且对该主题的研究还不够。评估韩国特应性儿童父母类固醇恐惧症的现状，并调查教育在减少类固醇恐惧症方面的重要性。采用结构式问卷对126名AD患儿家长进行了调查，其中父亲占22.2%，母亲占77.8%。在问卷管理后，所有参与者都接受了TCS使用的教育。总体而言，67.5%的父母表现出类固醇恐惧症。类固醇恐惧症与潜在不良事件的知识、TCS使用经验和治疗依从性之间存在统计学相关性（p<0.05）。类固醇恐惧症的父母对治疗的依从性往往较低。TCS最常见的不良反应是皮肤萎缩和变薄（71.9%）。导致类固醇恐惧症的最常见信息来源是互联网（49.2%）。类固醇恐惧症的风险因素是AD严重程度（比值比[OR]=5.332 [中度]，9.040 [重度] vs.轻度; p=0.001）和对潜在不良事件的了解（OR=2.658; p=0.021）。我们发现AD患者的父母中类固醇恐惧症的患病率很高，这里显示了这种恐惧症对治疗依从性的影响。我们强调皮肤科医生作为提供有关TCS使用的准确信息和适当教育的重要作用。
Topical corticosteroids (TCS) are the first-line agents for the treatment of atopic dermatitis (AD). However, a vague phobia concerning the use of TCS exists among parents of children with AD because of misinformation, and studies on the subject are insufficient. To assess the current state of steroid phobia among parents of atopic children in Korea and to investigate the importance of education in its reduction. By using a structured questionnaire, 126 parents of children with AD (22.2% fathers, 77.8% mothers) were interviewed. After the questionnaire administration, all participants were educated about TCS use. Overall, 67.5% of the parents showed steroid phobia. A statistical correlation was found between steroid phobia and knowledge of potential adverse events, experience of TCS use, and adherence to treatment (p<0.05). Adherence to treatment tended to be lower among parents with steroid phobia. The most recognized adverse effects of TCS were skin atrophy and thinning (71.9%). The most prevalent information source leading to steroid phobia was the Internet (49.2%). The risk factors for steroid phobia were AD severity (odds ratio [OR]=5.332 [moderate], 9.040 [severe] vs. mild; p=0.001) and the knowledge of potential adverse events (OR=2.658; p=0.021). We found a high prevalence of steroid phobia among parents of patients with AD, and here show the impact of this phobia on treatment adherence. We emphasize the important role of dermatologists as providers of accurate information and appropriate education about the use of TCS.