Computed Analysis of Three-Dimensional Cone-Beam Computed Tomography Angiography for Determination of Tumor-Feeding Vessels During Chemoembolization of Liver Tumor: A Pilot Study
Computed Analysis of Three-Dimensional Cone-Beam Computed Tomography Angiography for Determination of Tumor-Feeding Vessels During Chemoembolization of Liver Tumor: A Pilot Study
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DOI：
10.1007/s00270-010-9846-6
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发表时间：
2010-12-01
影响因子：
2.9
通讯作者：
de Baere, Thierry
中科院分区：
文献类型：
--
作者：
Deschamps, Frederic;Solomon, Stephen B.;de Baere, Thierry
本研究的目的是评价三维（3D）锥形束计算机断层扫描血管造影（CTA）的计算机分析，以确定亚段肿瘤供血血管（FV）。2008年1月至10月，18名连续患者接受了25例肝脏肿瘤的经动脉化疗栓塞（TACE）。（15例肝细胞癌[HCC]和10例神经内分泌转移）前后位投影血管造影（二维[2D]）和3D锥形束CTA图像通过注射肝总动脉逆行获得，FV由三名放射技术人员使用软件包（S）独立地识别，该软件包（S）通过分析3D图像自动确定FV。三位介入放射科医师（IR）通过回顾2D图像然后检查3D图像独立地识别FV。最后，FV数量和位置的“基本事实”是通过IR之间的共识获得的，IR被允许使用任何成像，包括2D，3D和所有倾斜或选择性血管造影来进行这种确定。评价3D和S结果，3D图像识别FV的灵敏度（73%）高于2D图像（64%）（P = 0.036）S的敏感性（93%）高于21。（P = 0.02）和3D（P = 0 0 0 5）成像3D成像的I期或回顾期长于2D成像（187 vs 94 s，P = 0.0001）或S（135 s，P = 0 0 0 0 1）二维和三维图像的IR符合率分别为5 4%和6 2%，而82%的这些初步数据表明，计算确定的FV是准确和敏感的。
The purpose of this study was to evaluate computed analysis of three-dimensional (3D) cone-beam computed tomography angiography (CTA) of the liver for determination of subsegmental tumor-feeding vessels (FVs) Eighteen consecutive patients underwent transarterial chemoembolization (TACE) from January to October 2008 for 25 liver tumors (15 hepatocellular carcinomas [HCCs] and 10 neuroendocrine metastases) Anteroposterior projection angiogram (two-dimensional [2D]) and 3D cone-beam CTA images were acquired by injection of the common hepatic artery Retrospectively, FVs were independently identified by three radiology technologists using a software package (S) that automatically determines FVs by analysis of 3D images Subsequently, three interventional radiologists (IRs) independently identified FVs by reviewing the 2D images followed by examination of the 3D images Finally, the "ground truth" for the number and location of FVs was obtained by consensus among the IRs who were allowed to use any imagingincluding 2D, 3D and all oblique or selective angiogramsfor such determination Sensitivities, durations, and degrees of agreement for review of 21), 3D, and S results were evaluated Sensitivity of 3D (73%) was higher than 2D (64%) images for identification of FVs (P = 0 036) The sensitivity of S (93%) was higher than 21) (P = 0 02) and 3D (P = 0 005) imaging The duration I or review of 3D imaging was longer than that for 2D imaging (187 vs 94 s, P = 0 0001) or for S (135 s, P = 0 0001) The degree of agreement between the IRs using 2D and 3D imaging were 54% and 62%, respectively whereas it was 82% between the three radiology technologists using S These preliminary data show that computed determination of FVs is both accurate and sensitive.