Towards fast and accurate temperature mapping with proton resonance frequency-based MR thermometry.
Towards fast and accurate temperature mapping with proton resonance frequency-based MR thermometry.
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DOI：
10.3978/j.issn.2223-4292.2012.01.06
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发表时间：
2012
影响因子：
2.8
通讯作者：
Madore B
中科院分区：
文献类型：
--
作者：
Yuan J;Mei CS;Panych LP;McDannold NJ;Madore B
成像温度的能力是MRI的一个非常有吸引力的特征，并且已经被积极地用于指导微创热治疗。在许多基于MR的温度敏感方法中，质子共振频率（PRF）测温提供了在大温度范围内信号与温度的良好线性的优点。此外，PRF偏移已被证明是相当独立的组织类型和热历史。由于这些原因，PRF方法已发展成为最广泛使用的基于MR的测温方法。在本论文中，将回顾基于PRF的温度映射的基本原理，沿着相关脉冲序列设计。将讨论旨在提高基于PRF的温度测量序列的成像速度和/或温度精度的技术进步，例如图像加速、脂肪抑制、减小的视场成像以及运动跟踪和校正。开发适用于脂肪含量不可忽略的运动器官的精确MR测温方法是一个非常具有挑战性的目标，但最近的发展表明，这一目标可能会实现。如果是这样的话，MR引导的热疗法可能会发挥越来越重要的治疗和姑息作用，作为一种微创手术的替代方案。
The capability to image temperature is a very attractive feature of MRI and has been actively exploited for guiding minimally-invasive thermal therapies. Among many MR-based temperature-sensitive approaches, proton resonance frequency (PRF) thermometry provides the advantage of excellent linearity of signal with temperature over a large temperature range. Furthermore, the PRF shift has been shown to be fairly independent of tissue type and thermal history. For these reasons, PRF method has evolved into the most widely used MR-based thermometry method. In the present paper, the basic principles of PRF-based temperature mapping will be reviewed, along with associated pulse sequence designs. Technical advancements aimed at increasing the imaging speed and/or temperature accuracy of PRF-based thermometry sequences, such as image acceleration, fat suppression, reduced field-of-view imaging, as well as motion tracking and correction, will be discussed. The development of accurate MR thermometry methods applicable to moving organs with non-negligible fat content represents a very challenging goal, but recent developments suggest that this goal may be achieved. If so, MR-guided thermal therapies may be expected to play an increasingly-important therapeutic and palliative role, as a minimally-invasive alternative to surgery.