Multislice Perfusion of the Kidneys Using Parallel Imaging: Image Acquisition and Analysis Strategies
Multislice Perfusion of the Kidneys Using Parallel Imaging: Image Acquisition and Analysis Strategies
复制标题
DOI：
10.1002/mrm.22387
复制
发表时间：
2010-06-01
影响因子：
3.3
通讯作者：
Francis, Susan T.
中科院分区：
文献类型：
--
作者：
Gardener, Alexander G.;Francis, Susan T.
血流敏感的交替反转恢复动脉自旋标记结合并行成像采集用于获取肾脏的单次激发、多层螺旋灌注图。对于基于顺序减影的动脉自旋标记方法来说，一个相当大的问题是由于采集之间的呼吸运动而引起的肾脏运动。研究了呼吸策略(自由呼吸、呼吸触发和屏气)的影响，并研究了背景抑制的使用。评估了通过图像配准进行运动校正的应用，并测量了灌注率。采集后图像重排可改善视觉质量和随后的血流灌注定量。使用这种校正，可以仅从自由呼吸采集数据，而不需要良好的呼吸轨迹，并且在最短的总体采集时间内，有利于患者的舒适度。在动脉自旋标记数据中加入背景抑制可以降低灌注信噪比并低估灌注。Magn Reson Med 63：1627-1636,2010。(C)2010年Wiley-Liss公司
Flow-sensitive alternating inversion recovery arterial spin labeling with parallel imaging acquisition is used to acquire single-shot, multislice perfusion maps of the kidney. A considerable problem for arterial spin labeling methods, which are based on sequential subtraction, is the movement of the kidneys due to respiratory motion between acquisitions. The effects of breathing strategy (free, respiratory-triggered and breath hold) are studied and the use of background suppression is investigated. The application of movement correction by image registration is assessed and perfusion rates are measured. Postacquisition image realignment is shown to improve visual quality and subsequent perfusion quantification. Using such correction, data can be collected from free breathing alone, without the need for a good respiratory trace and in the shortest overall acquisition time, advantageous for patient comfort. The addition of background suppression to arterial spin labeling data is shown to reduce the perfusion signal-to-noise ratio and underestimate perfusion. Magn Reson Med 63:1627-1636, 2010. (C) 2010 Wiley-Liss, Inc.