Highlights of the 2nd International Symposium on Tribbles and Diseases: tribbles tremble in therapeutics for immunity, metabolism, fundamental cell biology and cancer
Highlights of the 2nd International Symposium on Tribbles and Diseases: tribbles tremble in therapeutics for immunity, metabolism, fundamental cell biology and cancer
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第二届Tribbles与疾病国际研讨会亮点：tribbles在免疫、新陈代谢、基础细胞生物学和癌症治疗中颤抖
DOI：
10.1016/j.apsb.2018.12.007
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发表时间：
2019-03-01
影响因子：
14.5
通讯作者：
Hu, Zhuowei
中科院分区：
文献类型：
--
作者：
Cui, Bing;Eyers, Patrick A.;Hu, Zhuowei
Tribbles（TRIB）家族的假激酶蛋白已被证明在细胞周期、代谢疾病、慢性炎症性疾病和癌症发展中起关键作用。更好地理解TRIB假激酶的机制可以为疾病的发展提供新的见解，并有助于促进TRIB蛋白作为药物发现的新治疗靶点。在2018年5月7日至9日在中国北京举行的第二届Tribbles与疾病国际研讨会上，一组领先的Tribbles科学家报告了他们的发现和正在进行的关于不同TRIB蛋白在免疫，代谢，基础细胞生物学和癌症领域的影响的研究。在这里，我们总结了会议期间举行的4个主题演讲，13个全体演讲和8个简短会谈的重要和有见地的概述。这些发现可能为理解TRIB假激酶在各种疾病发展中的作用提供新的见解。(C)2019中国药学会、中国医学科学院药物研究所。由爱思唯尔公司制作和主持
The Tribbles (TRIB) family of pseudokinase proteins has been shown to play key roles in cell cycle, metabolic diseases, chronic inflammatory disease, and cancer development. A better understanding of the mechanisms of TRIB pseudokinases could provide new insights for disease development and help promote TRIB proteins as novel therapeutic targets for drug discovery. At the 2nd International Symposium on Tribbles and Diseases held on May 7-9, 2018 in Beijing, China, a group of leading Tribbles scientists reported their findings and ongoing studies about the effects of the different TRIB proteins in the areas of immunity, metabolism, fundamental cell biology and cancer. Here, we summarize important and insightful overviews from 4 keynote lectures, 13 plenary lectures and 8 short talks that took place during this meeting. These findings may offer new insights for the understanding of the roles of TRIB pseudokinases in the development of various diseases. (C) 2019 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V.