CFD Challenge: Predicting Patient-Specific Hemodynamics at Rest and Stress through an Aortic Coarctation
CFD Challenge: Predicting Patient-Specific Hemodynamics at Rest and Stress through an Aortic Coarctation
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CFD 挑战：通过主动脉缩窄预测患者在休息和应激状态下的特定血流动力学
DOI：
10.1007/978-3-642-54268-8_11
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发表时间：
2013
影响因子：
6.1
通讯作者：
Alain B. Lumsden
中科院分区：
文献类型：
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作者：
C. Karmonik;A. Brown;K. Debus;J. Bismuth;Alain B. Lumsden
这里介绍的工作是一个CFD挑战的一部分，调查潜在的计算流体动力学CFD模拟，以预测压力和流量在主动脉缩窄在应力时，其余情况下是已知的。在我们的方法中，我们选择耦合三元素Windkessel模型的出口边界条件。其余情况的流量和压力具有良好的再现性。在应力情况下，仅改变流入边界条件，基线压力过高，表明可能需要降低Windkessel模型中的总阻力。这相当于扩张血管，可能是药理学应激试验的结果。未来的工作需要开发一种优化策略来调整Windkessel数据以匹配临床结果。
The here presented work is part of a CFD challenge investigating the potential for computational fluid dynamics CFD simulations to predicted pressures and flows in an aortic coarctation during stress when conditions for the rest case are known. In our approach, we choose to couple a three element Windkessel model to the outlet boundary conditions. Good reproducibility of flow and pressures for the rest case were achieved. In the stress case, where only the inflow boundary condition was changed, baseline pressure was too high, indicating that the total resistance in the Windkessel models may need to be reduced. This would correspond to dilating the blood vessels as might be the result of a pharmacological stress test. Future work is needed to develop an optimization strategy to tune the Windkessel data for matching the clinical results.
DOI：
--
发表时间：
2005-10
期刊：
AJNR. American journal of neuroradiology
影响因子：
--
作者：
L. Jou;G. Wong;B. Dispensa;M. Lawton;R. Higashida;W. Young;D. Saloner
通讯作者：
L. Jou;G. Wong;B. Dispensa;M. Lawton;R. Higashida;W. Young;D. Saloner