Virophages to viromes: a report from the frontier of viral oceanography

Virophages to viromes: a report from the frontier of viral oceanography
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DOI:
10.1016/j.coviro.2011.05.003
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发表时间:
2011-07-01
影响因子:
5.9
通讯作者:
Culley, Alexander I.
Culley, Alexander I.
中科院分区:
医学2区
文献类型:
--
作者:
Culley, Alexander I.

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对海洋病毒的研究增进了我们对生态学、进化论、微生物学、海洋学和病毒学的理解。本综述讨论的重要发现包括发现具有扭曲病毒和细胞之间界限的基因组大小和代谢能力的巨型病毒、参与光合作用和细胞凋亡的病毒、检测所有基因组组成的病毒群落以及病毒在海洋微生物进化中的突出地位。尽管我们取得了巨大进展,但我们尚未将丰富的病毒基因组数据档案与海洋学过程综合起来。单病毒基因组学等尖端方法的发展现在提供了一套工具,可以更好地将病毒整合到海洋生态中。
The investigation of marine viruses has advanced our understanding of ecology, evolution, microbiology, oceanography and virology. Significant findings discussed in this review include the discovery of giant viruses that have genome sizes and metabolic capabilities that distort the line between virus and cell, viruses that participate in photosynthesis and apoptosis, the detection of communities of viruses of all genomic compositions and the preeminence of viruses in the evolution of marine microbes. Although we have made great progress, we have yet to synthesize the rich archive of viral genomic data with oceanographic processes. The development of cutting edge methods such as single virus genomics now provide a toolset to better integrate viruses into the ecology of the ocean.