Phylogeny of the large extrachromosomal DNA of organisms in the phylum Apicomplexa.
Phylogeny of the large extrachromosomal DNA of organisms in the phylum Apicomplexa.
复制标题
顶复门生物体大染色体外 DNA 的系统发育。
DOI：
10.1111/j.1550-7408.1995.tb01615.x
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发表时间：
1995
期刊：
影响因子：
--
通讯作者：
Lang-Unnasch,N
中科院分区：
文献类型：
--
作者：
Egea,N;Lang-Unnasch,N
Organisms in the phylum Apicomplexa appear to have a large extrachromosomal DNA which is unrelated to the mitochondrial DNA. Based on the apparent gene content of the large (35 kb) extrachromosomal DNA ofPlasmodium falciparum, it has been suggested that it is a plastid‐like DNA, which may be related to the plastid DNA of rhodophytes. However, phylogenetic analyses have been inconclusive. It has been suggested that this is due to the unusually high A + T content of thePlasmodium falciparumlarge extrachromosomal DNA. To further investigate the evolution of the apicomplexan large extrachromosomal DNA, the DNA sequence of the organellar ribosomal RNA gene fromToxoplasma gondii, was determined. TheToxoplasma gondiirDNA sequence was most similar to the large extrachromosomal rDNA ofPlasmodium falciparum, but was much less A + T rich. Phylogenetic analyses were carried out using the LogDet transformation to minimize the impact of nucleotide bias. These studies support the evolutionary relatedness of theToxoplasma gondiirDNA with the large extrachromosomal rDNA ofPlasmodium falciparumand with the organellar rDNA of another parasite in the phylum Apicomplexa,Babesia bovis.These analyses also suggest that the apicomplexan large extra‐chromosomal DNA may be more closely related to the plastid DNA of euglenoids than to those of rhodophytes.
