Group I allergens of grass pollen as cell wall-loosening agents
Group I allergens of grass pollen as cell wall-loosening agents
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DOI：
10.1073/pnas.94.12.6559
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发表时间：
1997-06-10
影响因子：
11.1
通讯作者：
Durachko, DM
中科院分区：
文献类型：
--
作者：
Cosgrove, DJ;Bedinger, P;Durachko, DM
I族过敏原是草花粉的主要过敏原，但其生物学功能尚不清楚。这些蛋白质在结构上与扩张蛋白相关，后者能够诱导植物细胞壁的延伸（蠕变）。玉米花粉提取物具有强大的扩张素样活性，通过壁伸展和壁应力松弛实验测量，这种活性对草细胞壁是选择性的，至少部分是由于玉米I族过敏原的作用，我们认为I族过敏原通过放松草柱头和花柱的细胞壁促进花粉管侵入母体组织。此外，在水稻、拟南芥和大豆的营养组织中存在相关mrna，这意味着过敏原同源物也可能在生长的营养组织中起到松弛壁的作用。
Group I allergens are the major allergens of grass pollen, but their biological function is unknown. These proteins are shown here to be structurally related to expansins, which are able to induce extension (creep) of plant cell walls. Extracts of maize pollen possess potent expansin-like activity, as measured in wall extension and wall stress-relaxation assays, This activity is selective for grass cell walls and is, at least partly, due to the action of maize group I allergens, We propose that group I allergens facilitate invasion of the pollen tube into the maternal tissues by loosening the cell walls of the grass stigma and style. Additionally, the presence of related mRNAs in vegetative tissues of rice, Arabidopsis, and soybean implies that allergen homologs may function to loosen walls in growing vegetative tissues as well.