A Microflow-Extraction System Using Double Tubes Having Different Inner Diameters in Tube Radial Distribution Phenomenon
A Microflow-Extraction System Using Double Tubes Having Different Inner Diameters in Tube Radial Distribution Phenomenon
复制标题
不同内径双管微流萃取系统的管径向分布现象
DOI：
10.15261/serdj.22.87
复制
发表时间：
2015
期刊：
影响因子：
--
通讯作者：
K. Tsukagoshi
中科院分区：
文献类型：
--
作者：
Katsuya Unesaki;M. Hashimoto;K. Tsukagoshi
当将具有两相分离特性的均相溶液（例如非离子表面活性剂水溶液）进料到开放管状毛细管中时，溶剂分子径向分布到管中，产生内相和外相。这就是所谓的“管径向分布现象”（TRDP）。在这项研究中，提出了一种新的微流萃取系统，使用双毛细管具有不同的内径在TRDP。这些管是内径为75和250 μ m的熔融石英毛细管;较小的管通过T型接头插入较大的管中。将含有12wt%Triton X-100作为非离子表面活性剂和2.4M氯化钾的均匀水溶液以20 μ L min-1的流速进料到较大的管中，其中管保持在34 ℃的温度下。管内均相水溶液转变为两相非均相溶液，富表面活性剂相在内相形成于管中部，含少量表面活性剂的水相在管壁附近形成为外相。在TRDP中，溶解在均匀溶液中的罗丹明B被分配到内表面活性剂富集相中。用明场显微镜-CCD照相机系统观察分布的罗丹明B（红色）。在本发明的微流萃取系统中，利用TRDP，含有罗丹明B的内相在较小的管内部流动，而外相在较小的管的尖端外部流动到较大的管中，所述较大的管使用具有不同内径的双毛细管制成。这一观察结果表明，溶解在均匀溶液中的罗丹明B通过基于TRDP的特定微流体行为的双毛细管被分离或萃取到内表面活性剂富集相中。
When homogeneous solutions that feature two-phase separation properties, such as a non-ionic surfactant aqueous solution, are fed into an open-tubular capillary tube, the solvent molecules are radially distributed into the tube, generating inner and outer phases. This is called “tube radial distribution phenomenon” (TRDP). In this study, a novel microflow-extraction system was proposed using double capillary tubes having different inner diameters in the TRDP. The tubes were fused-silica capillary tubes with a 75 and 250 m inner diameter; the smaller tube was inserted into the larger one through a T-type joint. A homogeneous aqueous solution containing 12 wt% Triton X-100 as a non-ionic surfactant and 2.4 M potassium chloride was fed into the larger tube at a flow rate of 20 L min -1 , where the tube was maintained at a temperature of 34°C. The homogeneous aqueous solution changed to a heterogeneous solution with two phases in the tube; the surfactant-rich phase was generated in the middle of the tube as an inner phase, while the aqueous phase containing a little of the surfactant was formed near the tube wall as an outer phase. In the TRDP Rhodamine B dissolved in the homogeneous solution was distributed into the inner surfactant-rich phase. The distributed Rhodamine B (red color) was observed with a bright-field microscope-CCD camera system. In the present microflow-extraction system, taking advantage of the TRDP, the inner phase containing Rhodamine B flowed inside the smaller tube, while the outer phase flowed outside the tip of the smaller tube into the larger tube, which was made using double capillary tubes having different inner diameters. This observation showed that Rhodamine B dissolved in the homogeneous solution was separated or extracted into the inner surfactant-rich phase through the double capillary tubes based on the specific microfluidic behavior of the TRDP.