STRUCTURE AND ENERGETICS OF PROTEIN CARBOHYDRATE COMPLEXES
STRUCTURE AND ENERGETICS OF PROTEIN CARBOHYDRATE COMPLEXES
复制标题
DOI：
10.1016/s0959-440x(94)90170-8
复制
发表时间：
1994-10-01
影响因子：
6.8
通讯作者：
TOONE, EJ
中科院分区：
文献类型：
--
作者：
TOONE, EJ
在过去的一年里，出现了几个新的蛋白质-碳水化合物复合物坐标集。这些数据分为两个重要类别：除豆类和趋化蛋白之外的凝集素复合物，以及允许放置离散水分子的高分辨率细化。这些数据应该有助于更好地理解水在蛋白质-碳水化合物络合中的作用。人们对缔合能量学的兴趣日益浓厚，并且现在可用于许多蛋白质-碳水化合物络合的热力学参数的量热测定。讨论了最近的结构和能量研究对蛋白质-碳水化合物关联模型的影响。
During the past year, several new coordinate sets for protein-carbohydrate complexes have appeared. The data fall into two important categories: complexes of lectins other than legume and chemotaxis proteins, and high-resolution refinements that allow placement of discrete water molecules. These data should lead to a better understanding of the role of water in protein-carbohydrate complexation. Interest in the energetics of association is growing, and calorimetrically determined thermodynamic parameters are now available for a host of protein-carbohydrate complexations. The impact of recent structural and energetic studies on proposed models of protein-carbohydrate association is discussed.