CONDITIONING OF LEG POSITION IN NORMAL AND MUTANT DROSOPHILA
CONDITIONING OF LEG POSITION IN NORMAL AND MUTANT DROSOPHILA
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DOI：
10.1073/pnas.78.6.3940
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发表时间：
1981-01-01
期刊：
影响因子：
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通讯作者：
QUINN, WG
中科院分区：
文献类型：
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作者：
BOOKER, R;QUINN, WG
个体黑腹鼠，无论有没有头，都可以接受训练，抬起腿以避免触电。这一行为类似于之前在完整的无头蟑螂身上展示的操作性条件反射。超过90%的无头野生果蝇学会了这一标准。突变体(Dunce、卷心菜和萝卜)最初是因为未能在嗅觉辨别范式中学习而被选中的，在这种新的学习环境中表现很差。正常果蝇和突变果蝇在学习行为上的差异在个体之间是可以区分的，这可能对镶嵌分析有用。
Individual D. melanogaster, with or without heads, can be trained to lift their legs to avoid electric shock. This behavior is similar to the operant conditioning previously demonstrated in intact and headless cockroaches. More than 90% of headless wild-type flies learned to the criterion. Mutants (dunce, cabbage and turnip), originally selected for failure to learn in an olfactory discrimination paradigm, performed poorly in this new learning situation. The difference in learning behavior between normal and mutant flies is distinguishable in individuals and may be useful for mosaic analysis.