Domain-constrained generation of clinical condition sets to help test computer-based clinical guidelines.
Domain-constrained generation of clinical condition sets to help test computer-based clinical guidelines.
复制标题
领域约束的临床条件集生成有助于测试基于计算机的临床指南。
DOI：
10.1136/jamia.2001.0080131
复制
发表时间：
2001
期刊：
影响因子：
--
通讯作者：
Miller,PL
中科院分区：
文献类型：
--
作者：
Miller,PL
本文介绍了T/Gen，一个原型的基于计算机的工具，旨在帮助维护知识的基于计算机的临床实践指南，提供patientspecific的建议。T/Gen将一组指南必须做出反应的临床条件作为输入，并允许用户指定特定于领域的约束，以确定哪些条件组合没有意义或不需要对彼此进行详尽的测试。T/Gen自动生成临床条件组合的约束集，每个约束集对应于一个临床病例（或几个密切相关的临床病例），可用于帮助测试基于计算机的指南。这些组合可以用于使用T/Gen的内置逻辑解释器来测试指南逻辑，或者生成一组用于测试操作指南系统的测试用例。T/Gen已经开发并测试了五个试点指南，用于两个儿童免疫系列，流感疫苗接种，初级甲状腺筛查和胚胎移植。本文介绍了T/Gen的方法是如何实施的五个试点指南，概述了该项目的现状和未来的方向，并讨论了在开展工作的过程中出现的设计问题。
The paper describes T/Gen, a prototype computer-based tool designed to help maintain the knowledge in a computer-based clinical practice guideline that provides patientspecific recommendations. T/Gen takes as input a set of clinical conditions to which a guideline must react, and allows the user to specify domain-specific constraints as to which combinations of conditions do not make sense or do not need to be exhaustively tested against one another. T/Gen automatically generates constrained sets of combinations of clinical conditions, each corresponding to a clinical case (or to several closely related clinical cases) that can be used to help test the computer-based guideline. The combinations can be used to test the guideline logic using T/Gen's built-in logic interpreter, or to generate a set of test cases for use in testing an operational guideline system. T/Gen has been developed and tested with five pilot guidelines, for two childhood immunization series, for influenza vaccination, for primary thyroid screening, and for embryo transplantation. The paper describes how T/Gen's approach is implemented for the five pilot guidelines, outlines the current status and future directions of the project, and discusses the design issues that arose in the course of carrying out the work.