A bibliometric analysis of research on (R)-ketamine from 2002 to 2021

A bibliometric analysis of research on (R)-ketamine from 2002 to 2021
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DOI:
10.1016/j.neuropharm.2022.109207
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发表时间:
2022-08-08
期刊:
影响因子:
4.7
通讯作者:
Yang, Chun
Yang, Chun
中科院分区:
医学2区
文献类型:
--
作者:
He, Teng;Wang, Di;Yang, Chun

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麻醉剂氯胺酮是含有等量(R)-氯胺酮和(S)-氯胺酮的外消旋混合物。越来越多的临床前数据表明,(R)-氯胺酮具有快速起效和持续的抗抑郁药,无明显副作用。目前有许多关于(R)-氯胺酮的研究,但这些研究的数量和质量尚不清楚。因此,我们对2002年1月至2021年12月关于(R)-氯胺酮的研究进行了文献计量学分析。我们在此期间从Web of Science数据库中获得了有关(R)-氯胺酮的出版物。收集了各种书目要素,包括年度出版物、作者、国家/地区、机构、期刊和关键词。本研究共纳入922篇出版物。日本千叶大学Kenji Hashimoto教授是(R)-氯胺酮领域最具影响力的作者,美国作者是该领域的领导者。此外,我们发现(R)-氯胺酮的抗癫痫作用是近年来的研究热点。这项研究提供了对(R)-氯胺酮研究的全面分析,并强调了对(R)-氯胺酮及其抗抑郁作用的日益增长的兴趣。
Anesthetic ketamine is a racemic mixture containing equal amount of (R)-ketamine and (S)-ketamine. Increasing preclinical data show that (R)-ketamine has a rapid-onset and sustained antidepressant without significant side effects. There are currently many studies on (R)-ketamine, however, the quantity and quality of these studies are unknown. Therefore, we conducted a bibliometric analysis of research on (R)-ketamine from January 2002 to December 2021. We obtained the publications on (R)-ketamine from the Web of Science database during the period. A variety of bibliographic elements were collected, including annual publications, authors, countries/ regions, institutions, journals, and keywords. A total of 922 publications were included in this study. Professor Kenji Hashimoto of Chiba University in Japan was the most productively influential author in the field of (R)-ketamine and the authors from United States were the leader in this field. In addition, we found that the anti-depressant effect of (R)-ketamine has been a hotspot in very recent years. This study provided a comprehensive analysis of research on (R)-ketamine and highlighted the growing interest in (R)-ketamine and its antidepressant effects.