Antibacterial Prophylaxis for Surgical Site Infection in the Elderly: Practical Application
Antibacterial Prophylaxis for Surgical Site Infection in the Elderly: Practical Application
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DOI：
10.1007/s40266-017-0471-9
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发表时间：
2017-07-01
期刊：
影响因子：
2.8
通讯作者：
Petrosillo, Nicola
中科院分区：
文献类型：
--
作者：
Cataldo, Maria Adriana;Granata, Guido;Petrosillo, Nicola
手术部位感染是最常见的卫生保健相关感染之一，与住院时间延长、再入院、死亡率增加和严重的经济负担有关。发生手术部位感染的危险因素包括与手术过程相关的变量以及宿主因素。年龄的增长与手术部位感染的发生有关。本综述的目的是提供抗生素预防老年人手术部位感染的最新进展。我们将重点放在具体问题和实际应用上，例如针对特定病例定殖菌群的敏感性模式靶向抗菌药物的重要性以及剂量调整的必要性。
Surgical site infections are among the most common healthcare-associated infections and are linked with increased length of hospitalization, re-admission, mortality and significant financial burden. Risk factors for the occurrence of surgical site infections include variables related to the surgical procedure as well as host factors. Increasing age is associated with the occurrence of surgical site infections. The aim of this review is to give an update on the antibiotic prophylaxis for surgical site infection in elderly people. We focused on specific issues and practical applications, such as the importance of targeting the antimicrobial agent to the susceptibility pattern of colonizing flora in selected cases and the need for dosage modifications.