Depressive Symptoms in Autistic Youth with Anxiety Disorders.
Depressive Symptoms in Autistic Youth with Anxiety Disorders.
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患有焦虑症的自闭症青少年的抑郁症状。
DOI：
10.1097/dbp.0000000000001223
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发表时间：
2023
期刊：
影响因子：
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通讯作者：
Storch,EricA
中科院分区：
文献类型：
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作者：
Greenberg,RebeccaL;Guzick,AndrewG;Schneider,SophieC;Weinzimmer,SairaA;Kook,Minjee;PerozoGarcia,AmandaB;Storch,EricA
目的：焦虑和抑郁常同时存在于青少年中，且两者的病因学存在重叠，但对孤独症青少年焦虑和抑郁的共病情况了解甚少。本研究探讨（1）抑郁症状的频率在自闭症儿童与临床显着的焦虑，（2）临床变量，可能与抑郁症状升高，（3）是否预处理抑郁症状预测认知行为疗法（CBT）outcomes for anxiety.Method：7至13岁的儿童（N= 87）和他们的父母参加了一项随机对照试验，比较2个版本的父母主导的，远程医疗提供的CBT程序。家长和孩子在治疗前后完成了各种临床评估和自我报告问卷。结果：57%的儿童样本报告出现抑郁症状加重，而大约20%的家长报告孩子的抑郁症状加重。焦虑和抑郁之间有很强的联系，孤独感的增加，每个孩子的报告，和功能障碍，每个家长的报告，被发现是唯一与抑郁症状升高。最后，抑郁症状是不是一个显着的预测CBT outcomes for anxiety.Conclusion：研究结果表明，自闭症儿童的焦虑和抑郁之间的高程度的共病，孤独，焦虑和功能障碍的感觉可能是情绪相关的问题的早期指标。需要进一步的研究来确定焦虑和抑郁之间的联系以及治疗自闭症儿童抑郁症的其他选择。
Objective:Anxiety and depression often coexist in youth and share overlapping symptomatology; however, little is known about the comorbidity of anxiety and depression in autistic youth. This study explores (1) the frequency of depressive symptoms among autistic children with clinically significant anxiety,(2) clinical variables that may be associated with elevated depressive symptoms, and (3) whether pretreatment depressive symptoms predict cognitive behavioral therapy (CBT) outcomes for anxiety.Method:Children aged 7 to 13 years (N= 87) and their parents participated in a randomized controlled trial comparing 2 versions of a parent-led, telehealth-delivered CBT program. Parents and children completed a variety of clinical assessments and self-report questionnaires before and after treatment.Results:Fifty-seven percent of the child sample reported experiencing elevated depressive symptoms while roughly 20% of parents reported elevated depressive symptoms in their child. A strong association between anxiety and depression was found. Heightened feelings of loneliness, per child report, and functional impairment, per parent report, were found to be uniquely associated with elevated depressive symptoms. Finally, depressive symptoms were not a significant predictor of CBT outcomes for anxiety.Conclusion:Findings suggest high degrees of comorbidity between anxiety and depression among autistic children and that feelings of loneliness, anxiety, and functional impairment may be early indicators of mood-related concerns. Further research is needed to determine the full extent of the association between anxiety and depression and additional options for treating depression in autistic children.