Healthy aging and disease: role for telomere biology?
Healthy aging and disease: role for telomere biology?
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DOI：
10.1042/cs20100385
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发表时间：
2011-05
期刊：
影响因子：
--
通讯作者：
van der Harst P
中科院分区：
文献类型：
--
作者：
Zhu H;Belcher M;van der Harst P
衰老是一个影响大多数细胞、生物体和物种的生物学过程。人类衰老与各种慢性疾病的易感性增加有关，包括心血管疾病、2型糖尿病、神经系统疾病和癌症。尽管在过去的二十年中取得了显着的进展，我们对衰老的生物学的理解仍然是不完整的。端粒生物学最近已成为衰老和疾病过程中的重要参与者。
Aging is a biological process that affects most cells, organisms and species. Human aging is associated with increased susceptibility to a variety of chronic diseases, including cardiovascular disease, Type 2 diabetes, neurological diseases and cancer. Despite the remarkable progress made during the last two decades, our understanding of the biology of aging remains incomplete. Telomere biology has recently emerged as an important player in the aging and disease process.