Risk drinking levels and sex are associated with cancer and liver, respiratory, and other medical conditions.
Risk drinking levels and sex are associated with cancer and liver, respiratory, and other medical conditions.
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DOI：
10.1016/j.dadr.2021.100007
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发表时间：
2021-12
期刊：
影响因子：
--
通讯作者：
McKee SA
中科院分区：
文献类型：
--
作者：
Verplaetse TL;Roberts W;Peltier MR;Zakiniaeiz Y;Burke C;Moore KE;Pittman B;McKee SA
我们用NESARC检查了过去一年医疗条件下的性别风险饮酒水平。与男性相比，女性疼痛和呼吸系统疾病的几率更大。与适度饮酒者相比，戒酒者更有可能患有某些疾病。酗酒的女性比酗酒的男性更容易患癌症。高风险饮酒可能与跨器官系统的疾病有关。大量饮酒与酒精相关健康后果的风险增加有关。在过去的15年里，女性的酒精消费量有所增加，女性更有可能因饮酒而遭受更严重的健康风险。我们的研究小组发现，与男性相比，患有AUD的女性更有可能报告呼吸系统疾病或癌症。这项分析试图通过使用新的2020年美国饮食指南的风险饮酒水平。来自美国国家酒精及相关疾病流行病学调查（NESARC-III; n = 36，309）的数据用于评估性别（女性与男性）和酒精风险饮酒水平（戒酒者，狂欢，重度，极端狂欢与适度饮酒）之间的关联，过去一年自我报告的医生确认的医疗条件）。女性在过去一年中出现疼痛、呼吸道或其他疾病的可能性是男性的1.5至2倍（比值比[OR]=1.46-2.11）。显著的相互作用表明，大量饮酒或极端酗酒的女性患癌症或其他疾病的可能性是男性的2 - 3倍（OR=1.95-2.69）。女性戒酒者比男性戒酒者更有可能有其他医疗条件（OR=1.77）。与我们之前的研究结果一致，结果表明，较高的饮酒风险水平与过去一年自我报告的医生确认的跨器官系统的医疗状况有关，特别是在女性中。在对有重大医疗状况的个人进行临床护理时，应考虑对高危饮酒者进行治疗。
We examined sex by risk drinking levels on past year medical conditions with NESARC. Females had greater odds of pain and respiratory conditions vs. males. Abstainers were more likely to have some medical conditions vs. moderate drinkers. Heavy drinking females were more likely to have cancers vs. heavy drinking males. Higher risk drinking may be associated with conditions spanning organ systems. Heavy alcohol use is associated with increased risk of alcohol-related health consequences. Alcohol consumption has increased in females in the last fifteen years and females are more likely to experience exacerbated health risks due to drinking. Our group identified that females with AUD were more likely to report respiratory conditions or cancers compared to their male counterparts. This analysis sought to further examine relationships between sex and alcohol use on medical conditions by using the new 2020 U.S. Dietary Guidelines risk drinking levels. Data from the U.S. National Epidemiologic Survey on Alcohol and Related Conditions (NESARC-III; n = 36,309) was used to evaluate associations between sex (female vs. male) and alcohol risk drinking levels (abstainer, binge, heavy, extreme binge vs. moderate drinking) on past year self-reported doctor-confirmed medical conditions). Females were 1.5 to 2 times more likely to have pain, respiratory, or other medical conditions in the past year (odds ratio [OR]=1.46–2.11) vs. males. Significant interactions demonstrated that heavy drinking females or extreme binge drinking females were 2 to 3 times more likely to have cancers or other conditions (OR=1.95–2.69) vs. males at the same risk drinking level. Female abstainers were more likely than male abstainers to have other medical conditions (OR=1.77). Consistent with our previous findings, results identify that higher risk drinking levels are associated with the presence of past year self-reported doctor-confirmed medical conditions spanning organ systems, particularly in females. Treatment for high-risk drinking should be considered in the clinical care of individuals with significant medical conditions.
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DOI：
10.1136/bmj.d671
发表时间：
2011-02-22
期刊：
BMJ (Clinical research ed.)
影响因子：
--
作者：
Ronksley PE;Brien SE;Turner BJ;Mukamal KJ;Ghali WA
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Ghali WA
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DOI：
10.1016/s0735-1097(99)00531-8
发表时间：
2000-01-01
影响因子：
24
作者：
Gaziano, JM;Gaziano, TA;Buring, JE
通讯作者：
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DOI：
10.1016/j.pbb.2013.09.008
发表时间：
2013-11
期刊：
Pharmacology, biochemistry, and behavior
影响因子：
--
作者：
Apkarian AV;Neugebauer V;Koob G;Edwards S;Levine JD;Ferrari L;Egli M;Regunathan S
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DOI：
10.1080/08964289.2016.1165174
发表时间：
2016-07
期刊：
Behavioral medicine (Washington, D.C.)
影响因子：
--
作者：
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通讯作者：
Upton RD