Mammalian glycosylation in immunity.
Mammalian glycosylation in immunity.
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DOI:
10.1038/nri2417
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发表时间:
2008-11
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影响因子:
--
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--
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Glycosylation produces a diverse and abundant repertoire of glycans, which are collectively known as the glycome. Glycans are one of the four fundamental macromolecular components of all cells, and are highly regulated in the immune system. Their diversity reflects their multiple biological functions that encompass ligands for proteinaceous of receptors known as lectins. Since the discovery that selectins and their glycan ligands are important for the regulation of leukocyte trafficking, it has been shown that additional features of the vertebrate immune system are also controlled by endogenous cellular glycosylation. This Review focuses on the emerging immunological roles of the mammalian glycome.
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影响因子:
32.4
作者:
Demotte, Nathalie;Stroobant, Vincent;van der Bruggen, Pierre
通讯作者:
van der Bruggen, Pierre
影响因子:
82.9
作者:
Blois, Sandra M.;Ilarregui, Juan M.;Arck, Petra C.
通讯作者:
Arck, Petra C.
DOI:
10.1073/pnas.0400851101
发表时间:
2004-04-20
影响因子:
11.1
作者:
Collins, BE;Blixt, O;Paulson, JC
通讯作者:
Paulson, JC
影响因子:
4.8
作者:
Dias-Baruffi, M;Zhu, H;Cummings, RD
通讯作者:
Cummings, RD
影响因子:
8.6
作者:
Baum, LG;Blackall, DP;Baldwin, GC
通讯作者:
Baldwin, GC