Neoplasms of the Hard Palate
Neoplasms of the Hard Palate
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DOI：
10.1016/j.joms.2013.08.019
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发表时间：
2014-03-01
影响因子：
1.9
通讯作者：
Uslu, Sabri
中科院分区：
文献类型：
--
作者：
Aydil, Utku;Kizil, Yusuf;Uslu, Sabri
目的：虽然口腔最常见的肿瘤性病变是鳞状细胞癌（SCC），但硬腭的原发性肿瘤性病变迄今尚未得到系统的回顾。本研究的目的是确定硬腭肿瘤的组织病理学组成和特征。材料和方法：对1985年至2012年在作者所在机构治疗的66例硬腭原发性肿瘤患者进行回顾性分析。人口统计学特征，恶性率，组织病理学特征和分布，TNM分期结果，转移模式，和管理策略进行了investigated.Results：样本由66例患者（平均年龄，45.0岁，57.6%的男性）。良性肿瘤占57.6%，恶性肿瘤占42.4%。分别有52例（78.8%）和14例（21.2%）患者出现上皮肿瘤和间叶肿瘤。小涎腺肿瘤（MSGTs）是最常见的组织病理学类型（60.6%），其次是良性间叶肿瘤（15.2%）、SCC（12.1%）、恶性黑色素瘤（6.1%）、淋巴瘤（3.0%）和肉瘤（3.0%）。虽然75.0%的恶性上皮性肿瘤是在晚期，有没有pN+SCC或恶性MSGTcases.Conclusion：最常见的肿瘤硬腭MSGTs。SCC在该系列中相对罕见。虽然四分之三的肿瘤处于晚期，颈部转移不是位于硬腭的恶性上皮肿瘤的特征。(C)2014年美国口腔颌面外科医师协会
Purpose: Although the most common neoplastic lesion of the oral cavity is squamous cell carcinoma (SCC), primary neoplastic lesions of the hard palate have not been systematically reviewed to date. The aim of this study was to determine the histopathologic composition and characteristics of neoplasms of the hard palate.Materials and Methods: A retrospective analysis of 66 patients with a primary neoplasm of the hard palate managed at the authors' institution from 1985 through 2012 was performed. Demographic features, malignancy rate, histopathologic characteristics and distribution, TNM staging results, metastasis patterns, and management strategies were investigated.Results: The sample was composed of 66 patients (mean age, 45.0 yr; 57.6% men). Neoplasms were benign in 57.6% of cases and malignant in 42.4%. Epithelial neoplasms and mesenchymal neoplasms were encountered in 52 patients (78.8%) and 14 patients (21.2%), respectively. Minor salivary gland tumors (MSGTs) were the most common histopathologic group (60.6%), followed by benign mesenchymal tumors (15.2%), SCCs (12.1%), malignant melanomas (6.1%), lymphomas (3.0%), and sarcomas (3.0%). Although 75.0% of malignant epithelial neoplasms were at an advanced stage, there were no pN+SCC or malignant MSGT cases at presentation.Conclusion: The most common neoplasms of the hard palate were MSGTs. SCCs were relatively rare in this series. Although three-fourths of neoplasms were at an advanced stage, neck metastasis was not a characteristic of malignant epithelial neoplasms located in the hard palate. (C) 2014 American Association of Oral and Maxillofacial Surgeons