Transport of glucosamine (aldohexoses) by preimplantation mouse blastocysts.

Transport of glucosamine (aldohexoses) by preimplantation mouse blastocysts.
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植入前小鼠囊胚转运葡萄糖胺(己醛糖)。

DOI:
10.1016/0005-2736(82)90060-8
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发表时间:
1982
期刊:
Biochimica et biophysica acta
影响因子:
--
通讯作者:
R. Acey
R. Acey
中科院分区:
--
文献类型:
--
作者:
D. Dabich;R. Acey

文献摘要

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A carrier-mediated system for uptake of glucosamine (and other aldohexoses) was identified in preimplantation mouse blastocysts. With early and late blastocysts, the values forKm(525±82 and 651±137μM, respectively) andV(0.29±0.02 and 0.29±0.04 pmol/h per ng protein, respectively) for glucosamine are statistically indistinguishable. The same carrier system, therefore, is operative at the two developmental stages. Glucosamine uptake was temperature sensitive and inhibited by structural analogues and phloretin.