Viewing and annotating sequence data with Artemis.
Viewing and annotating sequence data with Artemis.
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DOI：
10.1093/bib/4.2.124
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发表时间：
2003-06-01
影响因子：
9.5
通讯作者：
Rutherford, Kim
中科院分区：
文献类型：
--
作者：
Berriman, Matt;Rutherford, Kim
Artemis是一种广泛使用的用于注释和查看序列数据的软件工具。使用Artemis不需要数据库。相反，单个序列数据文件可以在几乎没有格式要求的情况下进行分析，这使得它特别适合于小型基因组和染色体的研究，并且新手用户也能很容易上手。自1999年发布以来，Artemis已被用于注释各种各样的原核和真核基因组，从天蓝色链霉菌到最近的大部分恶性疟原虫基因组。Artemis允许轻松浏览注释后的基因组，并能简单地向原始序列数据添加有用的生物学信息。本文概述了Artemis的一些特性，包括它如何促进手动基因预测以及如何提供整个染色体或小型紧凑基因组的概况——这对于发现诸如致病岛等异常特征是很有用的。
Artemis is a widely used software tool for annotating and viewing sequence data. No database is required to use Artemis. Instead, individual sequence data files can be analysed with little or no formatting, making it particularly suited to the study of small genomes and chromosomes, and straightforward for a novice user to get started. Since its release in 1999, Artemis has been used to annotate a diverse collection of prokaryotic and eukaryotic genomes, ranging from Streptomyces coelicolor to, more recently, a large proportion of the Plasmodium falciparum genome. Artemis allows annotated genomes to be easily browsed and makes it simple to add useful biological information to raw sequence data. This paper gives an overview of some of the features of Artemis and includes how it facilitates manual gene prediction and can provide an overview of entire chromosomes or small compact genomes - useful for uncovering unusual features such as pathogenicity islands.