Innovations in Practice: A randomised controlled feasibility trial of Behavioural Activation as a treatment for young people with depression
Innovations in Practice: A randomised controlled feasibility trial of Behavioural Activation as a treatment for young people with depression
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DOI：
10.1111/camh.12415
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发表时间：
2020-07-28
影响因子：
6.1
通讯作者：
Ekers, David
中科院分区：
文献类型：
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作者：
Kitchen, Charlotte E. W.;Tiffin, Paul A.;Ekers, David
背景行为激活（BA）治疗可有效减轻成人抑郁症状，并且比更复杂的疗法更具成本效益。最近两项关于BA治疗年轻人抑郁症的系统综述强调了在这一领域进行更多研究的必要性。方法为了评估BA治疗青少年抑郁症的可接受性以及在儿童和青少年心理健康服务（CAMHS）中进行这种干预试验的可行性，将来自三个站点的22名患者随机分配到BA或常规CAMHS护理。现有的CAMHS工作人员接受了培训，通过简短的课程提供手动干预。治疗后，年轻人和他们的父母/照顾者被要求完成反馈调查。在3个月和6个月随访时评估症状和功能。该试验在ISRCTN登记研究中注册（参考：ISRCTN 52147450;）。结果通过对大量CAMHS服务用户的筛选，达到了招募目标。参与青少年的干预依从性很高（完成BA课程的中位数为7/8）。治疗后有初步的改善建议; BA组在积极方向上发生了很大的变化，但不包括常规护理，通过对抑郁、自尊和功能指标的平均分数进行视觉比较观察到。未报告不良事件。结论：研究结果表明，在这种情况下，BA是可以接受的，值得通过一个充分的动力随机对照试验进行评价。
Background Behavioural Activation (BA) treatment effectively reduces symptoms of depression in adults and is more cost-effective than more complex therapies. Two recent systematic reviews of BA for depression in young people highlighted the need for more studies in this area. Methods In order to evaluate the acceptability of BA treatment for adolescents with depression and the feasibility of conducting a trial of this intervention in Child and Adolescent Mental Health Services (CAMHS), 22 patients from across three sites were randomised to BA or usual CAMHS care. Existing CAMHS staff were trained to deliver the manualised intervention via a brief course. Following treatment, young people and their parents/carers were asked to complete a feedback survey. Symptoms and functioning were assessed at 3- and 6-month follow-up. The trial was registered with the ISRCTN Registry (ref: ISRCTN52147450; ). Results Recruitment targets were achieved through screening large numbers of CAMHS service users. Intervention adherence by the participating adolescents was high (median number of completed BA sessions was seven out of a total of eight). There were tentative suggestions of improvements following treatment; a large change in a positive direction for the BA group, but not for usual care, was observed by visual comparisons of mean scores on measures of depression, self-esteem and functioning. No adverse events were reported. Conclusions The findings suggest that BA in this setting is acceptable and warrants evaluation via a fully powered randomised controlled trial.