Foxn4 -: a new member of the forkhead gene family is expressed in the retina

Foxn4 -: a new member of the forkhead gene family is expressed in the retina
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DOI:
10.1016/s0925-4773(01)00465-8
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发表时间:
2001-09-01
影响因子:
2.6
通讯作者:
Smith, HK
Smith, HK
中科院分区:
生物学4区
文献类型:
--
作者:
Gouge, A;Holt, J;Smith, HK

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我们报告的克隆和表达的一种新的小鼠叉头/翅螺旋家族成员-Foxn 4,在视网膜,腹侧后脑和脊髓和背侧中脑的神经发育过程中表达。视网膜Foxn 4表达与增殖祖细胞区相关。在小鼠突变型眼发育迟缓(或(J))中,视网膜中的Foxn 4表达显著降低并过早终止。(C)2001爱思唯尔科学爱尔兰有限公司保留所有权利。
We report the cloning and expression of a novel murine forkhead/winged helix family member - Foxn4 that is expressed during neural development in the retina, the ventral hindbrain and spinal cord and dorsal midbrain. Retinal Foxn4 expression is associated with the zone of proliferating progenitor cells. In the Mouse mutant ocular retardation (or(J)), Foxn4 expression in the retina is significantly reduced and terminates prematurely. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.