The Concordance Index C and the Mann-Whitney Parameter Pr(X>Y) with Randomly Censored Data
The Concordance Index C and the Mann-Whitney Parameter Pr(X>Y) with Randomly Censored Data
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DOI：
10.1002/bimj.200800228
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发表时间：
2009-07-01
影响因子：
1.7
通讯作者：
Jia, Zhenyu
中科院分区：
文献类型：
--
作者：
Koziol, James A.;Jia, Zhenyu
Harrell的C指数或协调性C被广泛用于衡量两种生存分布的分离。在没有删节数据的情况下，c指数估计Mann-Whitney参数Pr(X>；Y)，该参数在各种统计背景下被重复使用。在随机删失数据存在的情况下，c指数不再估计Pr(X&>Y)；而是一个涉及基本删失分布的参数。这与Efron对Mann-Whitney参数的最大似然估计形成了对比，后者是在随机审查设置中推荐的。
Harrell's c-index or concordance C has been widely used as a measure of separation of two survival distributions. In the absence of censored data, the c-index estimates the Mann-Whitney parameter Pr(X>Y), which has been repeatedly utilized in various statistical contexts. In the presence of randomly censored data, the c-index no longer estimates Pr(X>Y); rather, a parameter that involves the underlying censoring distributions. This is in contrast to Efron's maximum likelihood estimator of the Mann-Whitney parameter, which is recommended in the setting of random censorship.