Effects of involuntary outpatient commitment and depot antipsychotics on treatment adherence in persons with severe mental illness.
Effects of involuntary outpatient commitment and depot antipsychotics on treatment adherence in persons with severe mental illness.
复制标题
非自愿门诊承诺和长效抗精神病药物对严重精神疾病患者治疗依从性的影响。
DOI：
10.1097/00005053-200109000-00003
复制
发表时间：
2001
期刊：
影响因子：
--
通讯作者：
Hiday,VA
中科院分区：
文献类型：
--
作者：
Swartz,MS;Swanson,JW;Wagner,HR;Burns,BJ;Hiday,VA
本研究探讨了在严重精神疾病患者的非自愿门诊承诺的研究过程中，治疗依从性的潜在改善。非自愿住院的受试者，在门诊承诺下等待出院，被随机分配出院后出院或继续门诊承诺。一个非随机组，最近的严重暴力史也进行了研究门诊承诺。随机对照组和门诊承诺组在治疗依从性的组间比较中没有显著差异。然而，对所有受试者（包括非随机暴力受试者）的分析显示，与那些只接受短暂门诊承诺或没有接受门诊承诺的受试者相比，那些接受持续门诊承诺（6个月或更长时间）的受试者更有可能坚持药物和其他治疗。长效抗精神病药的管理也显着提高治疗依从性独立的持续门诊承诺的影响。持续的门诊承诺可能会显着提高严重精神疾病患者对社区精神卫生治疗的依从性，从而有助于改善受依从性影响的其他临床结局。
This study examines potential improvement in treatment adherence during a study of involuntary outpatient commitment among individuals with severe mental illnesses. Involuntarily hospitalized subjects, awaiting discharge under outpatient commitment, were randomly assigned to be released or continue under outpatient commitment after hospital discharge. A nonrandomized group with a recent history of serious violence was also studied under outpatient commitment. Randomized control and outpatient commitment groups did not differ significantly in group comparisons of treatment adherence. However, analyses of all subjects, including nonrandomized violent subjects, showed that those who underwent sustained periods of outpatient commitment (6 months or more) were significantly more likely to remain adherent with medication and other treatment, compared with those who underwent only brief outpatient commitment or none. Administration of depot antipsychotics also significantly improved treatment adherence independently of the effect of sustained outpatient commitment. Sustained periods of outpatient commitment may significantly improve adherence with community-based mental health treatment for persons with severe mental illness and thus may help improve other clinical outcomes affected by adherence.