Physical activity in relation to knee cartilage T2 progression measured with 3 T MRI over a period of 4 years: data from the Osteoarthritis Initiative

Physical activity in relation to knee cartilage T2 progression measured with 3 T MRI over a period of 4 years: data from the Osteoarthritis Initiative
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DOI:
10.1016/j.joca.2013.06.022
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发表时间:
2013-10-01
影响因子:
7
通讯作者:
Link, T. M.
Link, T. M.
中科院分区:
医学2区
文献类型:
--
作者:
Lin, W.;Alizai, H.;Link, T. M.

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目的:本研究的目的是分析身体活动水平和膝关节早期退行性软骨变化之间的纵向关联,在没有OA临床或影像学证据的个体中使用4年内的12个松弛时间进行测量。设计:在骨关节炎倡议(OAI)的205名45-60岁的受试者中,在基线时以及2年和4年后测量了Carbonate T2。无膝关节疼痛的发病率和正常队列(西安大略和麦克马斯特大学骨关节炎指数(WOMAC)评分为0),Kellgren Lawrence(KL)评分为
Objective: The purpose of this study was to analyze the longitudinal association between physical activity levels and early degenerative cartilage changes in the knee, measured using 12 relaxation times over a period of 4 years in individuals without clinical or radiographic evidence of OA.Design: Cartilage T2 was measured at baseline and after 2 and 4 years in 205 subjects aged 45-60 years from the Osteoarthritis Initiative (OAI) incidence and normal cohorts with no knee pain (Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score of zero), and a Kellgren Lawrence (KL) score of