The medium latency muscle response to a vestibular perturbation is increased after depression of the cerebellar vermis.
The medium latency muscle response to a vestibular perturbation is increased after depression of the cerebellar vermis.
复制标题
DOI：
10.1002/brb3.782
复制
发表时间：
2017-10
影响因子：
3.1
通讯作者：
Bent LR
中科院分区：
文献类型：
--
作者：
Lam CK;Staines WR;Tokuno CD;Bent LR
前庭电刺激（GVS）能够在用于平衡的肌肉中唤起不同的反应。这些反射被称为短潜伏期（SL）和中潜伏期（ML）反应，可以通过感觉输入改变；当有额外的感官提示时，尺寸会减小。虽然我们对这些反应了解很多，但它们的起源和作用仍未完全了解。小脑是一种参与姿势控制和感觉整合的结构，它可能在这些反射的调节中发挥作用。采用连续θ波爆发刺激暂时抑制小脑蚓部，比较小脑抑制前后的前庭肌电图、力板剪切反应振幅。力板剪切振幅没有变化，骶髂肌反应无显著增加（p = 0.071），然而，我们确实发现小脑抑制后ML和整体前庭肌反应振幅显著增加（p = 0.026和p = 0.016）。当使用假性刺激时，没有引起任何变化。这些结果表明，小脑蚓部在调节前庭肌对GVS的反射反应中起作用。
Galvanic vestibular stimulation (GVS) is able to evoke distinct responses in the muscles used for balance. These reflexes, termed the short (SL) and medium latency (ML) responses, can be altered by sensory input; decreasing in size when additional sensory cues are available. Although much is known about these responses, the origin and role of the responses are still not fully understood. It has been suggested that the cerebellum, a structure that is involved in postural control and sensory integration, may play a role in the modulation of these reflexes. The cerebellar vermis was temporarily depressed using continuous theta burst stimulation and SL, ML and overall vestibular electromyographic and force plate shear response amplitudes were compared before and after cerebellar depression. There were no changes in force plate shear amplitude and a non‐significant increase for the SL muscle response (p = .071), however, we did find significant increases in the ML and overall vestibular muscle response amplitudes after cerebellar depression (p = .026 and p = .016, respectively). No changes were evoked when a SHAM stimulus was used. These results suggest that the cerebellar vermis plays a role in the modulation of vestibular muscle reflex responses to GVS.
登录
查看更多内容
影响因子：
5.5
作者：
Dakin, Christopher J.;Son, Gregory M. Lee;Blouin, Jean-Sebastien
通讯作者：
Blouin, Jean-Sebastien
影响因子：
5.5
作者：
Marsden, JF;Castellote, J;Day, BL
通讯作者：
Day, BL
影响因子：
5.5
作者：
FITZPATRICK, R;BURKE, D;GANDEVIA, SC
通讯作者：
GANDEVIA, SC
影响因子：
4.7
作者：
Koch, Giacomo;Mori, Francesco;Caltagirone, Carlo
通讯作者：
Caltagirone, Carlo
影响因子：
2
作者：
Lam, Chris K.;Tokuno, Craig D.;Bent, Leah R.
通讯作者：
Bent, Leah R.