Coding of intention in the posterior parietal cortex
Coding of intention in the posterior parietal cortex
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DOI：
10.1038/386167a0
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发表时间：
1997-03-13
期刊：
影响因子：
64.8
通讯作者：
Andersen, RA
中科院分区：
文献类型：
--
作者：
Snyder, LH;Batista, AP;Andersen, RA
为了看到或得到我们所看到的东西，来自视觉系统的空间信息必须转化为运动计划，后顶叶皮层（PPC）很好地完成了这一功能，因为它位于编码空间信息（1,2）的视觉区域和运动皮质区域之间。PPC包含几个细分，通常被认为是高阶感觉区域（3,4）。7a区和外侧顶叶内区的神经元在视觉引导的扫视前和扫视过程中放电。7a区和5区的其他神经元在视觉引导手臂运动之前和期间都是活跃的（5-10）。这些区域在记忆任务中也很活跃，在进行眼睛或手臂运动之前，动物会在数百毫秒内记住目标的位置。这种活动可以反映视觉注意力（11-15）或做出动作的意图（16-22）。这个问题很难解决，因为即使动物在将注意力引导到外围位置时保持固定，观察到的神经元活动也可能反映出计划但未执行的运动（22）。为了解决这个问题，我们记录了猴子计划到达或扫视到一个记忆中的位置时的PPC。我们现在报告说，对于大多数神经元来说，运动前的活动取决于所计划的运动类型。我们得出结论，PPC包含与动物打算做什么有关的信号。
To look at or reach for what we see, spatial information from the visual system must be transformed into a motor plan, The posterior parietal cortex (PPC) is well placed to perform this function, because it Lies between visual areas, which encode spatial information(1,2), and motor cortical areas. The PPC contains several subdivisions, which are generally conceived as high-order sensory areas(3,4). Neurons in area 7a and the lateral intraparietal area fire before and during visually guided saccades. Other neurons in areas 7a and 5 are active before and during visually guided arm movements(5-10). These areas are also active during memory tasks in which the animal remembers the location of a target for hundreds of milliseconds before making an eye or arm movement. Such activity could reflect either visual attention(11-15) or the intention to make movements(16-22). This question is difficult to resolve, because even if the animal maintains fixation while directing attention to a peripheral location, the observed neuronal activity could reflect movements that are planned but not executed(22). To address this, we recorded from the PPC while monkeys planned either reaches or saccades to a single remembered location. We now report that, for most neurons, activity before the movement depended on the type of movement being planned. We conclude that PPC contains signals related to what the animal intends to do.