Updated understanding of the outbreak of 2019 novel coronavirus (2019-nCoV) in Wuhan, China

Updated understanding of the outbreak of 2019 novel coronavirus (2019-nCoV) in Wuhan, China
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DOI:
10.1002/jmv.25689
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发表时间:
2020-02-12
影响因子:
12.7
通讯作者:
Wei, Fangqiang
Wei, Fangqiang
中科院分区:
医学3区
文献类型:
--
作者:
Wang, Weier;Tang, Jianming;Wei, Fangqiang

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帮助卫生工作者和公众以最新的认识快速、有效、从容地认识和应对2019年新型冠状病毒(2019-nCoV)。从2019年12月1日至2020年1月26日上午9:30(北京时间),在中国和世界各地的官方网站和公告上进行了全面搜索。绘制了2019-nCoV和当前疫情的最新摘要。截至2020年1月25日下午24时,内地中国共确诊1975例2019年新冠状病毒感染病例,共发生56例死亡。最近的死亡率约为2.84%,总共仍有2684例疑似病例。中国国家卫生委员会报告了截至2020年1月22日下午24时前17例死亡病例的详细情况。死亡病例包括13名男性和4名女性。死亡者的平均年龄为75岁(范围为48-89岁)。发烧(64.7%)和咳嗽(52.9%)是死亡者最常见的首发症状。从首发症状到死亡的中位天数为14.0天(6~41天),年龄在70岁及以上者(11.5天~19天)明显短于<70岁者(20天[10~41天;P=.033])。2019-nCoV感染正在蔓延,其发病率在全国范围内呈上升趋势。首批死亡病例主要发生在老年人中,其中疾病可能进展得更快。公众在应对病毒时仍应保持谨慎,更多关注保护老年人免受病毒侵袭。
To help health workers and the public recognize and deal with the 2019 novel coronavirus (2019-nCoV) quickly, effectively, and calmly with an updated understanding. A comprehensive search from Chinese and worldwide official websites and announcements was performed between 1 December 2019 and 9:30 am 26 January 2020 (Beijing time). A latest summary of 2019-nCoV and the current outbreak was drawn. Up to 24 pm, 25 January 2020, a total of 1975 cases of 2019-nCoV infection were confirmed in mainland China with a total of 56 deaths having occurred. The latest mortality was approximately 2.84% with a total of 2684 cases still suspected. The China National Health Commission reported the details of the first 17 deaths up to 24 pm, 22 January 2020. The deaths included 13 males and 4 females. The median age of the people who died was 75 (range 48-89) years. Fever (64.7%) and cough (52.9%) were the most common first symptoms among those who died. The median number of days from the occurence of the first symptom to death was 14.0 (range 6-41) days, and it tended to be shorter among people aged 70 years or more (11.5 [range 6-19] days) than those aged less than 70 years (20 [range 10-41] days; P = .033). The 2019-nCoV infection is spreading and its incidence is increasing nationwide. The first deaths occurred mostly in elderly people, among whom the disease might progress faster. The public should still be cautious in dealing with the virus and pay more attention to protecting the elderly people from the virus.