OUTCOME AND PROGNOSIS OF PATIENTS WITH CHRONIC FATIGUE VS CHRONIC FATIGUE SYNDROME
OUTCOME AND PROGNOSIS OF PATIENTS WITH CHRONIC FATIGUE VS CHRONIC FATIGUE SYNDROME
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DOI：
10.1001/archinte.155.19.2105
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发表时间：
1995-10-23
影响因子：
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通讯作者：
BUCHWALD, D
中科院分区：
文献类型：
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作者：
BOMBARDIER, CH;BUCHWALD, D
背景：关于慢性疲劳（CF）或CF综合征（CFS）患者的自然史和预后的数据很少。因此，我们比较了每种条件下的患者的功能结果，并测试了各种预后指标的有效性。方法：四百四十五（89%）的498个连续转诊患者进行了调查，平均为1.5年后，初步评估。从最初的评估数据被用来预测outcomes.Results：64%的所有患者报告改善，但只有2%的报告症状完全解决。最初诊断为CFS的患者在随访时报告的症状严重程度和功能水平低于CF患者。严重抑郁症预测CF组的失业率。年龄较大、病程较长和心境恶劣的终生病史预测CF组的改善较少。目前的心境恶劣预测CFS group.Conclusions改善较少：CFS的情况下，根据疾病控制和预防中心的定义确定慢性疲劳患者预后较差。在三级护理环境中，CF或CFS的恢复很少见，但改善很常见。两组的预后指标各不相同，但心境恶劣共存通常表明预后较差。
Background: There are few data on the natural history and prognosis of persons with chronic fatigue (CF) or CF syndrome (CFS). Therefore, we compared functional outcomes in patients with each condition and tested the validity of various prognostic indicators.Methods: Four hundred forty-five (89%) of 498 consecutive referral patients were surveyed an average of 1.5; years after an initial evaluation. Data from the initial evaluation were used to predict outcomes.Results: Sixty-four percent of all patients reported improvement, but only 2% reported complete resolution of symptoms. Patients initially diagnosed as having CFS reported greater symptom severity and lower level of functioning at follow-up than did patients with CF. Major depression predicted unemployment in the CF group. Older age, longer duration of illness, and a lifetime history of dysthymia predicted less improvement in the CF group. Current dysthymia predicted less improvement for the CFS group.Conclusions: The case definition of CFS according to the Centers for Disease Control and Prevention identifies chronically fatigued patients with poorer prognosis. In a tertiary care setting, recovery from CF or CFS is rare, but improvement is common. Prognostic indicators vary for the two groups, but the coexistence of dysthymia suggests poorer outcomes generally.