Mouse and cockroach allergens in the dust and air in northeastern United States inner-city public high schools
Mouse and cockroach allergens in the dust and air in northeastern United States inner-city public high schools
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DOI：
10.1111/j.1600-0668.2005.00363.x
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发表时间：
2005-08-01
期刊：
影响因子：
5.8
通讯作者：
Perzanowski, MS
中科院分区：
文献类型：
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作者：
Chew, GL;Correa, JC;Perzanowski, MS
考虑到高中生醒着的大部分时间都在学校环境中度过，这可能是暴露于室内过敏原的重要位置。我们调查了美国东北部一个主要城市11所学校的尘埃和空气中老鼠和蟑螂过敏原的水平。在整个学年中，从87间教室中抽取了三次尘埃样本。在5天的时间里，53名学生从他们的学校和家中收集了两个单独的空气样本（流量= 2.5 lpm）。不同学校粉尘中小鼠过敏原（MUP）含量差异较大，几何平均值在0.21 ~ 133 μ g/g之间。在81%的样本中检测到小鼠过敏原。蟑螂变应原（Bla g 2）低于检出限（< 0.003 μ g/g）至1.1 μ g/g。71%的粉尘样品检出蟑螂过敏原（> 0.003 μ g/g）。在22%的学校空气样本中检测到bla2。相比之下，小鼠过敏原仅检测到5%。这些结果表明，学校可能是小鼠和蟑螂接触过敏原的重要场所，是在整体过敏原干预策略中应考虑的室内环境。
Considering that high school students spend a large proportion of their waking hours in the school environment, this could be an important location for exposure to indoor allergens. We have investigated the levels of mouse and cockroach allergens in the settled dust and air from 11 schools in a major northeastern US city. Settled dust samples were vacuumed from 87 classrooms, three times throughout the school year. Two separate air samples (flow = 2.5 lpm) were collected by 53 students over a 5-day period from both their school and their home. Mouse allergen (MUP) in the dust varied greatly between schools with geometric means ranging from 0.21 to 133 mu g/g. Mouse allergen was detectable in 81% of the samples collected. Cockroach allergen (Bla g 2) ranged from below limit of detection (< 0.003 mu g/g) to 1.1 mu g/g. Cockroach allergen was detected (> 0.003 mu g/g) in 71% of the dust samples. Bla g 2 was detected in 22% of airborne samples from the schools. By comparison, mouse allergen was only detected in 5%. These results indicate that the school may be an important location for exposure to allergens from mice and cockroaches and is an indoor environment that should be considered in an overall allergen intervention strategy.